DrugDashboards

Systane Ultra

Polyethylene Glycol 400 and Propylene Glycol · POLYETHYLENE GLYCOL 400 4 mg/mL; PROPYLENE GLYCOL 3 mg/mL · Solution/ Drops · Ophthalmic · Alcon Laboratories, Inc.

NDC 00065-1431-41 · 2 BOTTLE, DROPPER in 1 CARTON / 10 mL in 1 BOTTLE, DROPPER · OTC MONOGRAPH DRUG · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. The price has held steady around $0.8454 per mL over the past year. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.8454per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Federal contracts pay (FSS)$14.10per package of 2X10MLAlcon Vision, LLC · Sep 24, 2020

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

$0$0.5$1.00Nov 2013Sep 2026$0.8454
72 price points · per MLSource: CMS NADAC

Medicaid spend (2025)

$24,040
1,218 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

30Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 1 active manufacturer+30

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for polyethylene glycol 400, propylene glycol (other) in the next 90 days

sole-source market · 2 Class I/II recall(s) in 12 months · price up 1% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M018
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Polyethylene Glycol 400 and Propylene Glycol (Solution/ Drops)

LabelerStrengthFirst seenLast seen
Alcon Laboratories, Inc.POLYETHYLENE GLYCOL 400 4 mg/mL; PROPYLENE GLYCOL 3 mg/mLJul 15, 2026Sep 3, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Systane Ultra — NDC 00065-1431-41," retrieved September 3, 2026, https://drugdashboards.com/drug/00065143141.

Free to cite with attribution — see how the data is put together.