DrugDashboards

Kaletra

Lopinavir and Ritonavir · LOPINAVIR 200 mg/1; RITONAVIR 50 mg/1 · Tablet, Film Coated · Oral · AbbVie Inc.

NDC 00074-6799-22 · 120 TABLET, FILM COATED in 1 BOTTLE · NDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $8.30 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$8.30per EAinvoice-surveyed acquisition cost · May 22, 2024
  • Part D plans paid (avg)$7.96per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$8.21per unitnegotiated price across 22 plans — before rebates · Apr 1, 2024
  • Medicaid generic ceiling (FUL)$5.90per TABweighted avg manufacturer price $3.3707 · Jun 1, 202571% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$8.21per unit
middle half $8.21$8.35 · 22 plans · Apr 1, 2024
Est. net of rebates
$4.93–$6.16
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 2 quarters since 2024.

NADAC price per unit

$0$5.00$10.00Feb 2013May 2024$8.30
19 price points · per EA · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$249.12
#90 count
$747.37

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2024)

$119,694
105 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

15Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5
  • manufacturer plans to discontinue+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for lopinavir and ritonavir (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $1,124.87 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA021906
TE code
AB
Approval date
Oct 28, 2005
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Kaletra, Tablet, 100 mg; 25 mg (NDC 0074-0522-60)Jul 24, 2026
  • Planned discontinuation Kaletra, Tablet, 100 mg; 25 mg (NDC 0074-3008-60)Jul 24, 2026
  • Planned discontinuation Kaletra, Tablet, 200 mg; 50 mg (NDC 0074-4014-12)Jul 24, 2026
  • Planned discontinuation Kaletra, Tablet, 200 mg; 50 mg (NDC 0074-6799-22)Jul 24, 2026

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Lopinavir and Ritonavir (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
AbbVie Deutschland GmbH & Co KgLOPINAVIR 100 mg/1; RITONAVIR 25 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.LOPINAVIR 200 mg/1; RITONAVIR 50 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.LOPINAVIR 100 mg/1; RITONAVIR 25 mg/1Jul 15, 2026Sep 2, 2026
Laurus Labs LimitedLOPINAVIR 200 mg/1; RITONAVIR 50 mg/1Jul 15, 2026Sep 2, 2026
Laurus Labs LimitedLOPINAVIR 100 mg/1; RITONAVIR 25 mg/1Jul 15, 2026Sep 2, 2026
Macleods Pharmaceuticals LimitedLOPINAVIR 200 mg/1; RITONAVIR 50 mg/1Jul 15, 2026Sep 2, 2026
Macleods Pharmaceuticals LimitedLOPINAVIR 100 mg/1; RITONAVIR 25 mg/1Jul 15, 2026Sep 2, 2026
AbbVie Deutschland GmbH & Co KgLOPINAVIR 200 mg/1; RITONAVIR 50 mg/1Jul 15, 2026Aug 31, 2026
AbbVie Inc.LOPINAVIR 200 mg/1; RITONAVIR 50 mg/1Jul 15, 2026Aug 29, 2026
AbbVie Inc.LOPINAVIR 100 mg/1; RITONAVIR 25 mg/1Jul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Kaletra — NDC 00074-6799-22," retrieved September 3, 2026, https://drugdashboards.com/drug/00074679922.

Free to cite with attribution — see how the data is put together.