DrugDashboards

Tresiba

insulin degludec · INSULIN DEGLUDEC 100 U/mL · Injection, Solution · Subcutaneous · Novo Nordisk

NDC 00169-2662-11 · 1 VIAL, GLASS in 1 CARTON / 10 mL in 1 VIAL, GLASS · BLA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price has fallen 72% in a year, to $9.02 per mL — and generics that get this cheap tend to get abandoned rather than defended. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$9.02per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$32.17per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$9.07per unitnegotiated price across 1,307 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$92.86per package of 10MLNovo Nordisk Inc. · Jan 28, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$9.07per unit
middle half $9.02$9.10 · 1,307 plans · Apr 1, 2026
Est. net of rebates
$5.44–$6.80
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
24%of plans cover it
tier 3 · prior auth 1% · step therapy 0% · qty limit 7%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$20.00$40.00Aug 2019Sep 2026$9.02
33 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$94.29
Reported to Texas DSHS · 2026 annual filing · Novo Nordisk Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$1.4M
2,927 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

35Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 3 active manufacturers+10
  • price down 72% year over year+15
  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for insulin degludec (injectable) in the next 90 days

sterile injectable · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 3 across plans
  • Costs ≥ $950/fill · avg $649.83 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
BLA203314
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Insulin Degludec, Injection, 10 mL Insulin Degludec vial (NDC 73070-400-11)Jul 21, 2025
  • Planned discontinuation Insulin Degludec, Injection, 3 mL Insulin Degludec 100 units/mL (U-100) FlexTouch® (NDC 73070-403-15)Jul 21, 2025
  • Planned discontinuation Insulin Degludec, Injection, 3 mL Insulin Degludec 200 units/mL (U-200) FlexTouch® (NDC 73070-503-15)Jul 21, 2025

Recalls (this NDC)

  • Class I · TerminatedMar 22, 2021
    Novo Nordisk IncTemperature Abuse: product samples were stored at temperatures below 32* F which is not in accordance with storage requirements that could cause a lack of efficacy and damage to the cartridge and pen-injectors.
  • Class I · TerminatedMar 22, 2021
    Novo Nordisk IncTemperature Abuse: product samples were stored at temperatures below 32* F which is not in accordance with storage requirements that could cause a lack of efficacy and damage to the cartridge and pen-injectors.
  • Class I · TerminatedMar 22, 2021
    Novo Nordisk IncTemperature Abuse: product samples were stored at temperatures below 32* F which is not in accordance with storage requirements that could cause a lack of efficacy and damage to the cartridge and pen-injectors.

Manufacturers of insulin degludec (Injection, Solution)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsINSULIN DEGLUDEC 200 U/mLJul 15, 2026Sep 3, 2026
Novo NordiskINSULIN DEGLUDEC 100 U/mLJul 15, 2026Sep 3, 2026
A-S Medication SolutionsINSULIN DEGLUDEC 100 U/mLJul 15, 2026Sep 2, 2026
Novo NordiskINSULIN DEGLUDEC 200 U/mLJul 15, 2026Sep 2, 2026
Novo Nordisk Pharma, Inc.INSULIN DEGLUDEC 200 U/mLJul 15, 2026Sep 2, 2026
Novo Nordisk Pharma, Inc.INSULIN DEGLUDEC 100 U/mLJul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Tresiba — NDC 00169-2662-11," retrieved September 3, 2026, https://drugdashboards.com/drug/00169266211.

Free to cite with attribution — see how the data is put together.