DrugDashboards

Levothyroxine Sodium

levothyroxine sodium · LEVOTHYROXINE SODIUM 88 ug/1 · Tablet · Oral · Mylan Pharmaceuticals Inc.

NDC 00378-1807-10 · 1000 TABLET in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

7 companies supply this market — a reasonable cushion if one runs into trouble. The generic price is down 17% over the past year, to $0.0502 per unit. The brand (levothyroxine sodium) runs $1.35 per unit 24× more. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0502per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.0923per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$0.1646per unitnegotiated price across 5,496 plans — before rebates · Apr 1, 2026
  • Medicaid generic ceiling (FUL)$0.1509per TABweighted avg manufacturer price $0.0862 · Aug 1, 2026301% of what pharmacies pay — higher than 90% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.1646per unit
middle half $0.1084$0.2539 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.1646
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.2$0.4$0.6Nov 2013Sep 2026$0.0502
155 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$1.50
#90 count
$4.51

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$218,408
19,739 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • Class I/II recall on same molecule/form in past 12 months+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for levothyroxine sodium (oral solid) in the next 90 days

16 Class I/II recall(s) in 12 months · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA076187
TE code
AB1,AB2,AB3,AB4
Approval date
Jun 5, 2002
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · OngoingNov 18, 2024
    Viatris IncSuperpotent Drug and Subpotent Drug: potency failures obtained
  • Class II · TerminatedMar 15, 2021
    Cardinal Health Inc.CGMP Deviations: Intermittent exposure to temperature excursion during storage.

Manufacturers of levothyroxine sodium (Tablet)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsLEVOTHYROXINE SODIUM .088 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 150 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .1 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .025 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .137 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 25 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 88 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .125 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .075 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 75 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 112 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .112 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 125 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM .15 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 100 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 50 ug/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsLEVOTHYROXINE SODIUM 200 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 100 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 125 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 150 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 112 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 75 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 200 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 50 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 88 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 25 ug/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackLEVOTHYROXINE SODIUM 300 ug/1Jul 15, 2026Sep 3, 2026
Northwind Health Company, LLCLEVOTHYROXINE SODIUM 88 ug/1Jul 15, 2026Sep 3, 2026
Northwind Health Company, LLCLEVOTHYROXINE SODIUM 50 ug/1Jul 15, 2026Sep 3, 2026
Northwind Health Company, LLCLEVOTHYROXINE SODIUM 112 ug/1Jul 15, 2026Sep 3, 2026
Northwind Health Company, LLCLEVOTHYROXINE SODIUM 175 ug/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals, Inc.LEVOTHYROXINE SODIUM .075 mg/1Aug 27, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.LEVOTHYROXINE SODIUM 50 ug/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.LEVOTHYROXINE SODIUM 88 ug/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.LEVOTHYROXINE SODIUM 100 ug/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.LEVOTHYROXINE SODIUM 50 ug/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.LEVOTHYROXINE SODIUM 25 ug/1Jul 15, 2026Sep 3, 2026
Preferred Pharmaceuticals Inc.LEVOTHYROXINE SODIUM 175 ug/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPLEVOTHYROXINE SODIUM .112 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPLEVOTHYROXINE SODIUM 100 ug/1Jul 15, 2026Sep 3, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Levothyroxine Sodium — NDC 00378-1807-10," retrieved September 3, 2026, https://drugdashboards.com/drug/00378180710.

Free to cite with attribution — see how the data is put together.