DrugDashboards

Valsartan and Hydrochlorothiazide

valsartan and hydrochlorothiazide · VALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 · Tablet, Film Coated · Oral · Mylan Pharmaceuticals Inc.

NDC 00378-6325-77 · 90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

10 companies supply this market — deep enough that no single failure threatens the supply. The generic price is down 10% over the past year, to $0.2007 per unit. The brand (Diovan HCT) runs $11.46 per unit 92× more. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.2007per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D point of sale (median)$0.4050per unitnegotiated price across 5,649 plans — before rebates · Jan 1, 2025
  • Medicaid generic ceiling (FUL)$0.2007per TABweighted avg manufacturer price $0.1116 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.4050per unit
middle half $0.2447$0.5387 · 5,649 plans · Jan 1, 2025
Est. net of rebates
≈ $0.4050
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 5 quarters since 2024.

NADAC price per unit

$0$1.00$2.00Nov 2013Sep 2026$0.2007
155 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$6.02
#90 count
$18.06

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$369,271
19,609 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for valsartan and hydrochlorothiazide (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA078020
TE code
AB
Approval date
Sep 21, 2012
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class II · OngoingDec 4, 2018
    Mylan Laboratories Limited, (Nashik FDF)GCMP Deviations: FDA analysis confirmed presence of trace amounts of an impurity, N-nitrosodiethylamine (NDEA) found in the API used to manufacture the product.
  • Class II · OngoingDec 4, 2018
    Mylan Laboratories Limited, (Nashik FDF)GCMP Deviations: FDA analysis confirmed presence of trace amounts of an impurity, N-nitrosodiethylamine (NDEA) found in the API used to manufacture the product.
  • Class II · OngoingDec 4, 2018
    Mylan Laboratories Limited, (Nashik FDF)GCMP Deviations: FDA analysis confirmed presence of trace amounts of an impurity, N-nitrosodiethylamine (NDEA) found in the API used to manufacture the product.
  • Class II · OngoingDec 4, 2018
    Mylan Laboratories Limited, (Nashik FDF)GCMP Deviations: FDA analysis confirmed presence of trace amounts of an impurity, N-nitrosodiethylamine (NDEA) found in the API used to manufacture the product.
  • Class II · OngoingDec 4, 2018
    Mylan Laboratories Limited, (Nashik FDF)GCMP Deviations: FDA analysis confirmed presence of trace amounts of an impurity, N-nitrosodiethylamine (NDEA) found in the API used to manufacture the product.
  • Class II · OngoingNov 20, 2018
    Mylan Pharmaceuticals Inc.CGMP Deviations: FDA lab confirmed presence an impurity, N-nitrosodiethylamine (NDEA) contained in the API used to manufacture the product.

Manufacturers of valsartan and hydrochlorothiazide (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
A-S Medication SolutionsVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Aurobindo Pharma LimitedVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 20, 2026Sep 3, 2026
Aurobindo Pharma LimitedVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 20, 2026Sep 3, 2026
Aurobindo Pharma LimitedVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 20, 2026Sep 3, 2026
Bryant Ranch PrepackVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
Northwind Health Company, LLCVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 3, 2026
A-S Medication SolutionsVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.VALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.VALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.VALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.VALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.VALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
AvKAREVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
AvKAREVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
AvKAREVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
AvKAREVALSARTAN 320 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
AvKAREVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackVALSARTAN 160 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackVALSARTAN 80 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1Aug 26, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Valsartan and Hydrochlorothiazide — NDC 00378-6325-77," retrieved September 3, 2026, https://drugdashboards.com/drug/00378632577.

Free to cite with attribution — see how the data is put together.