DrugDashboards

Saphris

Asenapine Maleate · ASENAPINE MALEATE 2.5 mg/1 · Tablet · Sublingual · Allergan, Inc.

NDC 00456-2402-60 · 6 CASE in 1 CARTON / 1 BLISTER PACK in 1 CASE / 10 TABLET in 1 BLISTER PACK · NDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. The brand price has held steady around $20.99 per unit over the past year. Generic versions run $2.93 per unit7.2× cheaper. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$20.99per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$19.61per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$22.67per unitnegotiated price across 44 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$903.21per package of 6X10Abbvie US LLC · Jan 1, 2026
  • Medicaid generic ceiling (FUL)$5.03per TABweighted avg manufacturer price $2.8723 · Aug 1, 202624% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$22.67per unit
middle half $22.36$22.99 · 44 plans · Apr 1, 2026
Est. net of rebates
$13.60–$17.01
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
1%of plans cover it
tier 4 · prior auth 50% · step therapy 50% · qty limit 5%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$10.00$20.00$30.00Mar 2016Sep 2026$20.99
34 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$629.83
#90 count
$1889.48

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$1.3M
1,355 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

5Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 5 active manufacturers+5

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for asenapine maleate (oral solid) in the next 90 days

sole-source market · price up 5% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 4 across plans
  • Costs ≥ $950/fill · avg $1,155.35 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA022117
TE code
AB
Approval date
Aug 13, 2009
Patents / exclusivity
12 patents, 0 exclusivities
TypeNumber / codeExpires
patent8022228*PEDOct 6, 2026
patent7741358*PEDOct 6, 2026
patent7741358*PEDOct 6, 2026
patent8022228*PEDOct 6, 2026
patent8022228*PEDOct 6, 2026
patent7741358*PEDOct 6, 2026
patent7741358Apr 6, 2026
patent7741358Apr 6, 2026
patent7741358Apr 6, 2026
patent8022228Apr 6, 2026
patent8022228Apr 6, 2026
patent8022228Apr 6, 2026

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class II · TerminatedMay 18, 2017
    Forest Laboratories, LLCLabeling; Label Mixup; blister lidding foil and shell-pack labeled as 10 mg but package actually contains 5 mg tablets

Manufacturers of Asenapine Maleate (Tablet)

LabelerStrengthFirst seenLast seen
Allergan, Inc.ASENAPINE MALEATE 5 mg/1Jul 15, 2026Sep 3, 2026
Breckenridge Pharmaceutical, Inc.ASENAPINE MALEATE 10 mg/1Jul 15, 2026Sep 3, 2026
Catalent U.k. Swindon Zydis LimitedASENAPINE MALEATE 5 mg/1Jul 15, 2026Sep 3, 2026
Msn Laboratories Private LimitedASENAPINE MALEATE 5 mg/1Jul 15, 2026Sep 3, 2026
Breckenridge Pharmaceutical, Inc.ASENAPINE MALEATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
Msn Laboratories Private LimitedASENAPINE MALEATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
Allergan, Inc.ASENAPINE MALEATE 2.5 mg/1Jul 15, 2026Aug 31, 2026
Allergan, Inc.ASENAPINE MALEATE 10 mg/1Jul 15, 2026Aug 31, 2026
Msn Laboratories Private LimitedASENAPINE MALEATE 10 mg/1Jul 15, 2026Aug 31, 2026
Breckenridge Pharmaceutical, Inc.ASENAPINE MALEATE 5 mg/1Jul 15, 2026Aug 28, 2026
Catalent UK Swindon Zydis LimitedASENAPINE MALEATE 10 mg/1Jul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Saphris — NDC 00456-2402-60," retrieved September 3, 2026, https://drugdashboards.com/drug/00456240260.

Free to cite with attribution — see how the data is put together.