Brompheniramine Maleate, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride · PHENYLEPHRINE HYDROCHLORIDE 2.5 mg/5mL; BROMPHENIRAMINE MALEATE 1 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 5 mg/5mL · Liquid · Oral · Edwards Pharmaceuticals, Inc
NDC 00485-0204-16 · 473 mL in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →
Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price is up 18% over the past year, to $0.0514 per mL. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →Some pressure is visible, but not much — here’s everything the score found to count.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market · price up 8% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Alternative Pharmacal Corporation | DEXTROMETHORPHAN HYDROBROMIDE 20 mg/5mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/5mL; BROMPHENIRAMINE MALEATE 4 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Edwards Pharmaceuticals, Inc | PHENYLEPHRINE HYDROCHLORIDE 2.5 mg/5mL; BROMPHENIRAMINE MALEATE 1 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 5 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Alternative Pharmacal Corporation | DEXTROMETHORPHAN HYDROBROMIDE 4 mg/5mL; PHENYLEPHRINE HYDROCHLORIDE 20 mg/5mL; BROMPHENIRAMINE MALEATE 10 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| Edwards Pharmaceuticals, Inc | PHENYLEPHRINE HYDROCHLORIDE 1 mg/5mL; BROMPHENIRAMINE MALEATE 5 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 2.5 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| Alternative Pharmacal Corporation | BROMPHENIRAMINE MALEATE 4 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 20 mg/5mL; PHENYLEPHRINE HYDROCHLORIDE 10 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
| Edwards Pharmaceuticals, Inc | BROMPHENIRAMINE MALEATE 1 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 5 mg/5mL; PHENYLEPHRINE HYDROCHLORIDE 2.5 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Rynex DM — NDC 00485-0204-16," retrieved September 3, 2026, https://drugdashboards.com/drug/00485020416.
Free to cite with attribution — see how the data is put together.