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Belladonna and Opium

ATROPA BELLADONNA and OPIUM · ATROPA BELLADONNA 16.2 mg/1; OPIUM 30 mg/1 · Suppository · Rectal · Padagis US LLC

NDC 00574-7045-12 · 12 PACKET in 1 BOX / 1 SUPPOSITORY in 1 PACKET · UNAPPROVED DRUG OTHER · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $20.84 per unit over the past year.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$10.00$20.00$30.00Oct 2013Jul 2019$20.84
13 price points · per · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$264.17
Reported to Texas DSHS · 2025 annual filing · Padagis US LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$8
12 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Regulatory

Application
TE code
Approval date
Patents / exclusivity

Shortage history

  • Planned discontinuation Belladonna and Opium, Suppository, 16.2 mg; 30 mg (NDC 0574-7045-04)Jul 23, 2026
  • Planned discontinuation Belladonna and Opium, Suppository, 16.2 mg; 30 mg (NDC 0574-7045-12)Jul 23, 2026
  • Planned discontinuation Belladonna and Opium, Suppository, 16.2 mg; 60 mg (NDC 0574-7040-04)Jul 23, 2026
  • Planned discontinuation Belladonna and Opium, Suppository, 16.2 mg; 60 mg (NDC 0574-7040-12)Jul 23, 2026

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of ATROPA BELLADONNA and OPIUM (Suppository)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackATROPA BELLADONNA 16.2 mg/1; OPIUM 30 mg/1Jul 15, 2026Sep 2, 2026
Padagis US LLCATROPA BELLADONNA 16.2 mg/1; OPIUM 30 mg/1Jul 15, 2026Sep 2, 2026
Padagis US LLCATROPA BELLADONNA 16.2 mg/1; OPIUM 60 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Belladonna and Opium — NDC 00574-7045-12," retrieved September 3, 2026, https://drugdashboards.com/drug/00574704512.

Free to cite with attribution — see how the data is put together.