DrugDashboards

Ampicillin

Ampicillin · AMPICILLIN TRIHYDRATE 500 mg/1 · Capsule · Oral · Sandoz Inc

NDC 00781-2145-05 · 500 CAPSULE in 1 BOTTLE · ANDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $0.4385 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00781-2145-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.4172per unit
middle half $0.3020$0.4631 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.4172
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.2$0.4$0.6Nov 2013Sep 2026$0.4385
151 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$13.16
#90 count
$39.47

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$7,146
522 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for ampicillin (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA064082
TE code
AB
Approval date
Aug 29, 1995
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Ampicillin (Capsule)

LabelerStrengthFirst seenLast seen
Aurobindo Pharma LimitedAMPICILLIN TRIHYDRATE 250 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedAMPICILLIN TRIHYDRATE 500 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.AMPICILLIN TRIHYDRATE 500 mg/1Jul 15, 2026Sep 2, 2026
Sandoz IncAMPICILLIN TRIHYDRATE 500 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Ampicillin — NDC 00781-2145-05," retrieved September 3, 2026, https://drugdashboards.com/drug/00781214505.

Free to cite with attribution — see how the data is put together.