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Desonide Ointment, 0.05%

Desonide Ointment, 0.05% · DESONIDE .5 mg/g · Ointment · Topical · Encube Ethicals, Inc.

NDC 21922-0004-07 · 1 TUBE in 1 CARTON / 60 g in 1 TUBE · ANDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price is down 21% over the past year, to $0.2672 per gram. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$1.00$2.00Nov 2019Sep 2026$0.2672
83 price points · per GMSource: CMS NADAC

Medicaid spend (2025)

$323,600
10,239 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

28Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 2 active manufacturers+20
  • price down 26% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for desonide (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA210998
TE code
AB
Approval date
Jan 30, 2019
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Desonide Ointment, 0.05% (Ointment)

LabelerStrengthFirst seenLast seen
Encube Ethicals, Inc.DESONIDE .5 mg/gJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackDESONIDE .5 mg/gJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Desonide Ointment, 0.05% — NDC 21922-0004-07," retrieved September 3, 2026, https://drugdashboards.com/drug/21922000407.

Free to cite with attribution — see how the data is put together.