DrugDashboards

Clobetasol Propionate

Clobetasol Propionate Ointment USP, 0.05% · CLOBETASOL PROPIONATE .5 mg/g · Ointment · Topical · Encube Ethicals, Inc.

NDC 21922-0017-07 · 1 TUBE in 1 CARTON / 60 g in 1 TUBE · ANDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price is down 29% over the past year, to $0.1124 per gram. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1124per GMinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$0.8627per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal contracts pay (FSS)$3.40per package of 60GMEncube Ethicals, Inc. · Nov 17, 2025

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.2$0.4$0.6Feb 2020Sep 2026$0.1124
80 price points · per GMSource: CMS NADAC

Medicaid spend (2025)

$2.3M
94,289 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

28Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 2 active manufacturers+20
  • price down 23% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for clobetasol propionate (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA211295
TE code
AB
Approval date
Nov 15, 2019
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Clobetasol Propionate Ointment USP, 0.05% (Ointment)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackCLOBETASOL PROPIONATE .5 mg/gJul 15, 2026Sep 3, 2026
Encube Ethicals, Inc.CLOBETASOL PROPIONATE .5 mg/gJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Clobetasol Propionate — NDC 21922-0017-07," retrieved September 3, 2026, https://drugdashboards.com/drug/21922001707.

Free to cite with attribution — see how the data is put together.