DrugDashboards

Ketoconazole

Ketoconazole Cream, 2% · KETOCONAZOLE 20 mg/g · Cream · Topical · Encube Ethicals, Inc.

NDC 21922-0025-05 · 1 TUBE in 1 CARTON / 30 g in 1 TUBE · ANDA · View full market →

The short version

8 companies supply this market — a reasonable cushion if one runs into trouble. The price is down 8% over the past year, to $0.2544 per gram. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 21922-0025-07) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.3565per unit
middle half $0.2531$0.3983 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.3565
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 87%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 5 quarters since 2024.

NADAC price per unit

$0$0.2$0.4$0.6Jun 2021Sep 2026$0.2544
64 price points · per GMSource: CMS NADAC

Medicaid spend (2025)

$2.4M
138,143 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for ketoconazole (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA212443
TE code
AB
Approval date
May 20, 2021
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Ketoconazole Cream, 2% (Cream)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsKETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
Asclemed Usa Inc.KETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
Encube Ethicals, Inc.KETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.KETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.KETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
Proficient Rx LPKETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
Remedyrepack Inc.KETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026
Sportpharm LLCKETOCONAZOLE 20 mg/gJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Ketoconazole — NDC 21922-0025-05," retrieved September 3, 2026, https://drugdashboards.com/drug/21922002505.

Free to cite with attribution — see how the data is put together.