DrugDashboards

Sodium Bicarbonate

Sodium Bicarbonate · SODIUM BICARBONATE 84 mg/mL · Injection, Solution · Intravenous · Exela Pharma Sciences, LLC

NDC 51754-8888-04 · 25 VIAL in 1 CARTON / 50 mL in 1 VIAL · ANDA · View full market →

The short version

19 companies supply this market — deep enough that no single failure threatens the supply. It is in shortage right now — FDA lists the reason as “other”. One of its named manufacturing plants, Exela Pharma Sciences, LLC., failed FDA inspectionwithin the last two years — the agency’s most serious outcome. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1540per MLinvoice-surveyed acquisition cost · Aug 12, 2026
  • Part D plans paid (avg)$0.2496per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.1$0.2Aug 2026Sep 2026$0.154
1 price point · per MLSource: CMS NADAC

Supply fragility

25● Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • related presentation in shortage+15
  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for sodium bicarbonate (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $66.59 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA211091
TE code
AP
Approval date
Jun 20, 2019
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation — Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-6637-14)Nov 7, 2025
  • In shortage now — Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 51754-5012-4)Jul 24, 2017
    month 110 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 63323-083-05)Jul 24, 2017
    month 110 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5001-5)Jul 24, 2017
    month 110 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5011-4)Jul 24, 2017
    month 110 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 63323-089-50)Jul 24, 2017
    month 110 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-01)Mar 1, 2017
    Other
    month 115 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-02)Mar 1, 2017
    Other
    month 115 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-14)Mar 1, 2017
    month 115 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-35)Mar 1, 2017
    Other
    month 115 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months
  • In shortage now — Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) Syringes (NDC 0409-6637-14)Mar 1, 2017
    Discontinuation of the manufacture of the drug
    month 115 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Sodium Bicarbonate (Injection, Solution)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 3, 2026
Exela Pharma Sciences, LLCSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 3, 2026
HF Acquisition Co LLC, DBA HealthFirstSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 3, 2026
Medical Purchasing Solutions, LLCSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 3, 2026
Amneal Pharmaceuticals Private LimitedSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals Private LimitedSODIUM BICARBONATE 12.6 mg/mLJul 15, 2026Sep 2, 2026
Anthea Pharma Private LimitedSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
CivicaSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Exela Pharma Sciences, LLCSODIUM BICARBONATE 75 mg/mLJul 15, 2026Sep 2, 2026
Exela Pharma Sciences, LLCSODIUM BICARBONATE 42 mg/mLJul 15, 2026Sep 2, 2026
Fresenius Kabi USA, LLCSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Fresenius Kabi USA, LLCSODIUM BICARBONATE 42 mg/mLJul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USASODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Henry Schein, Inc.SODIUM BICARBONATE 42 mg/mLJul 15, 2026Sep 2, 2026
Henry Schein, Inc.SODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLC.SODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Milla Pharmaceuticals Inc.SODIUM BICARBONATE 84 mg/mLAug 12, 2026Sep 2, 2026
Omnivium Pharmaceuticals Llc.SODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
ProPharma DistributionSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Steriscience Specialties Private LimitedSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Sun Pharmaceutical Industries LimitedSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
HF Acquisition Co LLC, DBA HealthFirstSODIUM BICARBONATE 42 mg/mLJul 15, 2026Aug 31, 2026
Hospira, Inc.SODIUM BICARBONATE 84 mg/mLJul 15, 2026Aug 31, 2026
Hospira, Inc.SODIUM BICARBONATE 42 mg/mLJul 15, 2026Aug 31, 2026
Baxter Healthcare CorporationSODIUM BICARBONATE 12.6 mg/mLAug 28, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Sodium Bicarbonate — NDC 51754-8888-04," retrieved September 3, 2026, https://drugdashboards.com/drug/51754888804.

Free to cite with attribution — see how the data is put together.