DrugDashboards

Alprazolam

Alprazolam · ALPRAZOLAM 2 mg/1 · Tablet · Oral · PD-Rx Pharmaceuticals, Inc.

NDC 55289-0523-60 · 60 TABLET in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

18 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00781-1089-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.1318per unit
middle half $0.0945$0.1995 · 5,408 plans · Apr 1, 2026
Est. net of rebates
≈ $0.1318
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
98%of plans cover it
tier 2 · prior auth 31% · step therapy 0% · qty limit 95%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for alprazolam (oral solid) in the next 90 days

sole-source market · 1 Class I/II recall(s) in 12 months

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA074909
TE code
AB
Approval date
Mar 25, 1998
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Alprazolam (Tablet)

LabelerStrengthFirst seenLast seen
Actavis Pharma, Inc.ALPRAZOLAM .25 mg/1Jul 15, 2026Sep 3, 2026
Actavis Pharma, Inc.ALPRAZOLAM 2 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCALPRAZOLAM 1 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCALPRAZOLAM .5 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedALPRAZOLAM .25 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedALPRAZOLAM 1 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackALPRAZOLAM 2 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackALPRAZOLAM .5 mg/1Jul 15, 2026Sep 3, 2026
Clinical Solutions Wholesale, LLCALPRAZOLAM 1 mg/1Jul 30, 2026Sep 3, 2026
Clinical Solutions Wholesale, LLCALPRAZOLAM 2 mg/1Jul 30, 2026Sep 3, 2026
Clinical Solutions Wholesale, LLCALPRAZOLAM .25 mg/1Jul 30, 2026Sep 3, 2026
Clinical Solutions Wholesale, LLCALPRAZOLAM .5 mg/1Jul 30, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.ALPRAZOLAM .25 mg/1Jul 15, 2026Sep 3, 2026
Pharmacia & Upjohn Company LlcALPRAZOLAM 1 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPALPRAZOLAM 2 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx Pharmacy of Tennessee, LLCALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingALPRAZOLAM .25 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.ALPRAZOLAM 2 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.ALPRAZOLAM .25 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.ALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
ANI Pharmaceuticals, Inc.ALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
Asclemed Usa Inc.ALPRAZOLAM 2 mg/1Jul 15, 2026Sep 2, 2026
Asclemed Usa Inc.ALPRAZOLAM .25 mg/1Jul 15, 2026Sep 2, 2026
Asclemed Usa Inc.ALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
Asclemed Usa Inc.ALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.ALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.ALPRAZOLAM 2 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.ALPRAZOLAM .25 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.ALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
AvPAKALPRAZOLAM .25 mg/1Jul 15, 2026Sep 2, 2026
AvPAKALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
AvPAKALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCALPRAZOLAM 1 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026
Direct_RxALPRAZOLAM 2 mg/1Jul 15, 2026Sep 2, 2026
Medsource PharmaceuticalsALPRAZOLAM .5 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Alprazolam — NDC 55289-0523-60," retrieved September 3, 2026, https://drugdashboards.com/drug/55289052360.

Free to cite with attribution — see how the data is put together.