DrugDashboards

Methotrexate

Methotrexate · METHOTREXATE SODIUM 2.5 mg/1 · Tablet · Oral · Alembic Pharmaceuticals Inc.

NDC 62332-0730-36 · 36 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

20 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.1566 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1566per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$19.76per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$0.1566per TABweighted avg manufacturer price $0.0449 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 16729-0486-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.4149per unit
middle half $0.2110$0.5609 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.4149
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 24% · step therapy 3% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.1$0.2Sep 2024Sep 2026$0.1566
25 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$4.70
#90 count
$14.09

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$174
12 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for methotrexate (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $1,035.57 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA217552
TE code
AB
Approval date
Jun 3, 2024
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Methotrexate (Tablet)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Accord Healthcare Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
AvKAREMETHOTREXATE SODIUM 2.5 mg/1Jul 29, 2026Sep 2, 2026
AvPAKMETHOTREXATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
Chartwell RX, LLCMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsMETHOTREXATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
Mylan Institutional Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Proficient Rx LPMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Safecor Health LLCMETHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Teva Pharmaceuticals USA, Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedMETHOTREXATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
Zydus Pharmaceuticals USA Inc.METHOTREXATE 2.5 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.METHOTREXATE SODIUM 2.5 mg/1Jul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Methotrexate — NDC 62332-0730-36," retrieved September 3, 2026, https://drugdashboards.com/drug/62332073036.

Free to cite with attribution — see how the data is put together.