pioglitazone and metformin hydrochloride · PIOGLITAZONE HYDROCHLORIDE 15 mg/1; METFORMIN HYDROCHLORIDE 850 mg/1 · Tablet, Film Coated · Oral · Takeda Pharmaceuticals America, Inc.
NDC 64764-0158-60 · 60 TABLET, FILM COATED in 1 BOTTLE, PLASTIC · NDA · View full market →
Only one company currently supplies this market — there is no backup if it stumbles. The price is up 13% over the past year, to $9.51 per unit.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Not scored — fragility is computed for NADAC-priced NDCs.
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
| Type | Number / code | Expires |
|---|---|---|
| patent | 9320714 | Feb 3, 2029 |
| patent | 9320714 | Feb 3, 2029 |
| patent | 9101660 | Jan 22, 2027 |
| patent | 9101660 | Jan 22, 2027 |
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Takeda Pharmaceuticals America, Inc. | PIOGLITAZONE HYDROCHLORIDE 15 mg/1; METFORMIN HYDROCHLORIDE 850 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Takeda Pharmaceuticals America, Inc. | PIOGLITAZONE HYDROCHLORIDE 850 mg/1; METFORMIN HYDROCHLORIDE 15 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Takeda Pharmaceuticals America, Inc. | METFORMIN HYDROCHLORIDE 850 mg/1; PIOGLITAZONE HYDROCHLORIDE 15 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Actoplus Met — NDC 64764-0158-60," retrieved September 3, 2026, https://drugdashboards.com/drug/64764015860.
Free to cite with attribution — see how the data is put together.