The short version
20 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Methotrexate
Methotrexate · METHOTREXATE 2.5 mg/1 · Tablet · Oral · Zydus Lifesciences Limited
NDC 70771-1058-09 · 90 TABLET in 1 BOTTLE · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for methotrexate (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- analysis · manufacture
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill · avg $1,035.57 per prescription
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program
Regulatory
- Application
- ANDA207812
- TE code
- AB
- Approval date
- Jan 13, 2017
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Methotrexate (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bryant Ranch Prepack | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| A-S Medication Solutions | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Accord Healthcare Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | METHOTREXATE SODIUM 2.5 mg/1 | Jul 29, 2026 | Sep 2, 2026 |
| AvPAK | METHOTREXATE 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | METHOTREXATE 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mylan Institutional Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mylan Pharmaceuticals Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Safecor Health LLC | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Teva Pharmaceuticals USA, Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | METHOTREXATE 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Pharmaceuticals USA Inc. | METHOTREXATE 2.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | METHOTREXATE SODIUM 2.5 mg/1 | Jul 15, 2026 | Aug 28, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Methotrexate — NDC 70771-1058-09," retrieved September 3, 2026, https://drugdashboards.com/drug/70771105809.
Free to cite with attribution — see how the data is put together.