The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Syfovre
Pegcetacoplan · PEGCETACOPLAN 15 mg/.1mL · Injection, Solution · Intravitreal · Apellis Pharmaceuticals, Inc.
NDC 73606-0020-02 · 1 VIAL, GLASS in 1 CARTON / 3 mL in 1 VIAL, GLASS · NDA · View full market →
One drug, every price
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
ⓘ How this was built
Data sources
- CMS NADAC (pharmacy acquisition, weekly)
- CMS Part B ASP quarterly payment limits
- CMS Maximum Fair Prices (IRA negotiated, NDC-level)
- Medicare Part D Spending by Drug (data.cms.gov, name-matched)
- VA FSS / Big4 federal contract prices (va.gov, twice monthly)
- ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
- California SB-17 WAC filings (list price, per package)
Method
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
- Medicare Part B pays (ASP+6%)$148.94per billing unit (1 MG)HCPCS J2781 · Jul 1, 2026
- Part D plans paid (avg)$22,307.17per dosage unitgross, before rebates — matched by drug name · 2024
- Federal ceiling (Big4)$1,602.94per unitAPL Sales I LLC · Jan 20, 2026
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$2,346.39
Reported to Texas DSHS · 2026 annual filing · Apellis Pharmaceuticals Inc
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Medicare Part B (ASP)
Payment limit per 1 MG
$148.944
HCPCS J2781 · Jul 1, 2026 quarter · typically ASP + 6%
Medicaid spend (2025)
$20,052
34 prescriptions paid by Medicaid nationally · all Medicaid spend →
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Where it's made
- Bachem AGSwitzerlandapi manufacture
- Eurofins Advantar Laboratories, LLCUnited Statesanalysis
- Eurofins Lancaster Laboratories, LLCUnited Statesanalysis
- api manufacture
- Lifecore Biomedical Operating Company, Inc.United Statesanalysis
- Lifecore Biomedical, LLCUnited Statesmanufacture
- Micro Measurement Laboratories, Inc.United Statesanalysis
- Packaging Coordinators, LLCUnited Statespack
- West Services and Solutions LLCUnited Statesanalysis
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 3 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill · avg $3,001.44 per prescription
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Empaveli
Regulatory
- Application
- NDA217171
- TE code
- —
- Approval date
- Feb 17, 2023
- Patents / exclusivity
- 13 patents, 2 exclusivities
| Type | Number / code | Expires |
|---|---|---|
| exclusivity | NCE | May 14, 2026 |
| exclusivity | NP | Feb 22, 2026 |
| patent | 12458695 | Dec 14, 2038 |
| patent | 11903994 | Feb 22, 2037 |
| patent | 12528836 | Oct 7, 2036 |
| patent | 10875893 | Nov 15, 2033 |
| patent | 10035822 | Nov 15, 2033 |
| patent | 11292815 | Nov 15, 2033 |
| patent | 10125171 | Aug 2, 2033 |
| patent | 11661441 | Jan 13, 2033 |
| patent | 7888323 | Dec 4, 2027 |
| patent | 7989589 | Dec 4, 2027 |
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Pegcetacoplan (Injection, Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Apellis Pharmaceuticals, Inc. | PEGCETACOPLAN 1080 mg/20mL | Jul 15, 2026 | Sep 2, 2026 |
| Apellis Pharmaceuticals, Inc. | PEGCETACOPLAN 15 mg/.1mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Syfovre — NDC 73606-0020-02," retrieved September 3, 2026, https://drugdashboards.com/drug/73606002002.
Free to cite with attribution — see how the data is put together.