DrugDashboards

Bupivacaine Hydrochloride

Bupivacaine Hydrochloride · BUPIVACAINE HYDROCHLORIDE 5 mg/mL · Injection, Solution · Epidural; Intracaudal; Perineural · Asclemed USA, Inc.

NDC 76420-0561-10 · 10 mL in 1 VIAL, SINGLE-DOSE · ANDA · View full market →

The short version

17 companies supply this market — deep enough that no single failure threatens the supply. It is in shortage right now — FDA lists the reason as “discontinuation of the manufacture of the drug”.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.6%chance of a new FDA shortage posting for bupivacaine hydrochloride (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA204842
TE code
AP
Approval date
Feb 11, 2021
Patents / exclusivity
None on file

Shortage history

  • In shortage now — Bupivacaine Hydrochloride PRESERVATIVE FREE, Injection, 2.5 mg/1 mL (NDC 72266-263-10)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 0.25%; 75 mg/30 mL (2.5 mg/mL) (NDC 0409-1159-10)Feb 20, 2018
    Discontinuation of the manufacture of the drug
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-1160-01)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1162-02)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-32)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-34)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-167-10)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-168-30)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-249-50)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-01)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-10)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-25)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-722-32)Feb 20, 2018
    Discontinuation of the manufacture of the drug
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-723-52)Feb 20, 2018
    Discontinuation of the manufacture of the drug
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 225 mg/30 mL (7.5 mg/mL) (NDC 0409-1165-02)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-1159-01)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 250 mg/50 mL (5 mg/mL) (NDC 0409-1163-01)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-32)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-34)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months
  • In shortage now — Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-169-10)Feb 20, 2018
    month 103 — 5× the typical 20-month injectable shortage · model puts 14% odds it resolves within 6 months

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Bupivacaine Hydrochloride (Injection, Solution)

LabelerStrengthFirst seenLast seen
Asclemed USA, Inc.BUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Eugia US LLCBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Eugia US LLCBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Fresenius Kabi USA, LLCBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
Henry Schein, Inc.BUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Henry Schein, Inc.BUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
Hikma Pharmaceuticals USA Inc.BUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
Hikma Pharmaceuticals USA Inc.BUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 3, 2026
Hikma Pharmaceuticals USA Inc.BUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 3, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
NorthStar RxLLCBUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 3, 2026
Onesource Specialty Pharma LimitedBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
Onesource Specialty Pharma LimitedBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 3, 2026
Onesource Specialty Pharma LimitedBUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 3, 2026
Xellia Pharmaceuticals USA LLCBUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 3, 2026
Xellia Pharmaceuticals USA LLCBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 3, 2026
A-S Medication SolutionsBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026
Anthea Pharma Private LimitedBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026
Anthea Pharma Private LimitedBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 2, 2026
Anthea Pharma Private LimitedBUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.BUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.BUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.BUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 2, 2026
Fosun Pharma USA Inc.BUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 2, 2026
Fosun Pharma USA Inc.BUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026
Fresenius Kabi USA, LLCBUPIVACAINE HYDROCHLORIDE 7.5 mg/mLJul 15, 2026Sep 2, 2026
Henry Schein, IncBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026
Henry Schein, IncBUPIVACAINE HYDROCHLORIDE 2.5 mg/mLJul 15, 2026Sep 2, 2026
HF Acquisition Co LLC, DBA HealthFirstBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 225 mg/30mLJul 15, 2026Sep 2, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 150 mg/30mLJul 15, 2026Sep 2, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 250 mg/50mLJul 15, 2026Sep 2, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 50 mg/10mLJul 15, 2026Sep 2, 2026
Hospira, Inc.BUPIVACAINE HYDROCHLORIDE 75 mg/30mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLCBUPIVACAINE HYDROCHLORIDE 5 mg/mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Bupivacaine Hydrochloride — NDC 76420-0561-10," retrieved September 3, 2026, https://drugdashboards.com/drug/76420056110.

Free to cite with attribution — see how the data is put together.