DrugDashboards

Cosopt Pf

dorzolamide hydrochloride and timolol maleate · DORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mL · Solution/ Drops · Ophthalmic · Thea Pharma Inc.

NDC 82584-0604-30 · 4 POUCH in 1 CARTON / 15 VIAL, SINGLE-DOSE in 1 POUCH / .2 mL in 1 VIAL, SINGLE-DOSE · NDA · View full market →

The short version

8 companies supply this market — a reasonable cushion if one runs into trouble. The brand price has held steady around $3.30 per unit over the past year. Generic versions run $1.13 per unit2.9× cheaper. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$3.30per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$3.21per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal contracts pay (FSS)$129.75per package of 60X0.2MLThea Pharma, Inc. · Jan 1, 2026
  • Medicaid generic ceiling (FUL)$1.71per MLweighted avg manufacturer price $0.9749 · Aug 1, 202652% of what pharmacies pay — a deeper discount than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 82584-0605-10) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$23.84per unit
middle half $23.84$23.84 · 2 plans · Apr 1, 2026
Est. net of rebates
$14.31–$17.88
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$2.00$4.00$6.00Jun 2023Sep 2026$3.30
26 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$206.66
Reported to Texas DSHS · 2026 annual filing · Thea Pharma, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$157,308
501 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • Class I/II recall on same molecule/form in past 12 months+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for dorzolamide hydrochloride and timolol maleate (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · 1 Class I/II recall(s) in 12 months

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA202667
TE code
AT2
Approval date
Feb 1, 2012
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of dorzolamide hydrochloride and timolol maleate (Solution/ Drops)

LabelerStrengthFirst seenLast seen
Thea Pharma Inc.DORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 3, 2026
A-S Medication SolutionsDORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedDORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Bausch & Lomb IncorporatedDORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackDORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Bryant Ranch PrepackDORZOLAMIDE HYDROCHLORIDE 22.3 mg/mL; TIMOLOL MALEATE 6.8 mg/mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedDORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Ingenus Pharmaceuticals, LLCDORZOLAMIDE HYDROCHLORIDE 20 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Micro Labs LimitedDORZOLAMIDE HYDROCHLORIDE 22.3 mg/mL; TIMOLOL MALEATE 6.8 mg/mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Cosopt Pf — NDC 82584-0604-30," retrieved September 3, 2026, https://drugdashboards.com/drug/82584060430.

Free to cite with attribution — see how the data is put together.