The short version
Only one company currently supplies this market — there is no backup if it stumbles. Historically, drugs in this position went on to a new shortage within 90 days about 0.4% of the time — roughly 3× the typical drug (0.1%).
Market view
alprostadil · Injection, Solution
2 marketed package NDCs · 1 active manufacturer
Most dispensed: 10 ug/mL · Injection, Powder, Lyophilized, For Solution · #2 blister packs/carton / 1 cartridge in 1 blister pack / 1 ml in 1 cartridge · 20 ug/mL · Injection, Powder, Lyophilized, For Solution · #2 blister packs/carton / 1 cartridge in 1 blister pack / 1 ml in 1 cartridge · 10 ug/.5mL · Injection, Powder, Lyophilized, For Solution · #2 syringes/carton / .5 ml in 1 syringe · 20 ug/.5mL · Injection, Powder, Lyophilized, For Solution · #2 syringes/carton / .5 ml in 1 syringe
What changed in the last 90 days
Every detected change for alprostadil, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- AlprostadilAug 26, 2026Mfr exitedBills Biotech pvt ltd. · alprostadil
- Caverject ImpulseAug 19, 2026Price upNADAC $106.2625 → $106.29955 per unit (+0.03%)
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 19, 2026New productApister Lifesciences Private Limited
- AlprostadilAug 15, 2026Mfr enteredApister Lifesciences Private Limited · alprostadil
Common questions
- Is Alprostadil in shortage right now?
- No. FDA does not currently list Alprostadil in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Alprostadil?
- 18 companies have marketed Alprostadil in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Alprostadil cost?
- The typical pharmacy pays about $170.42 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.