The short version
Only one company currently supplies this market — there is no backup if it stumbles. The price is up 10% over the past year, to $51.91 per mL.
Market view
estradiol cypionate · Injection
1 marketed package NDCs · 1 active manufacturer
Most dispensed: 5 mg/mL · Injection · #1 vial/carton / 5 ml in 1 vial
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $51.91 · middle half $51.91–$51.91 · full range $51.91–$51.91 · 1 products · 1 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for estradiol cypionate, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Estradiol CypionateJul 29, 2026Mfr exitedSCH Global Services Private Limited · estradiol cypionate
Same drug class
Other molecules FDA puts in Estrogen, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- aconiticum acidum, cis-, apis venenum purum, aquilegia vulgaris, bovista, cypripedium pubescens, estradiol, faecalis (alkaligenes), folliculinum, funiculus umbilicalis suis, glandula suprarenalis suis, heart (suis), hydrastis canadensis, hypophysis suis, kreosotum, lachesis mutus, lilium tigrinum, magnesia phosphorica, mercurius solubilis, mutabile bacillus (bach), oophorinum (suis), petroselinum sativum, pineal gland (suis), placenta totalis suis, progesterone, sepia, testosterone, uterus (suis)· 1 maker
- agnus castus, ambra grisea, estradiol, l-dopa, melatonin, petroselinum sativum, adenosinum triphosphoricum dinatrum, alpha-lipoicum acidum, nadidum, pantothenic acid, sarcolacticum acidum, ubidecarenonum, baryta carbonica, conium maculatum, selenium metallicum, folliculinum, testosterone, funiculus umbilicalis suis, glandula suprarenalis suis, hepar suis, hypothalamus suis, lymph node (suis), medulla ossis suis, oophorinum (suis), orchitinum (suis), pancreas suis, spleen (suis), human growth hormone,· 1 maker
- agnus castus, ambra grisea, estradiol, l-dopa, melatonin, petroselinum sativum, adenosinum triphosphoricum dinatrum, alpha-lipoicum acidum, nadidum, pantothenic acid, sarcolacticum acidum, ubidecarenonum, baryta carbonica, conium maculatum, selenium metallicum, folliculinum, testosterone, funiculus umbilicalis suis, glandula suprarenalis suis, hepar suis, hypothalamus suis, lymph node (suis), medulla ossis suis, oophorinum (suis), orchitinum (suis), pancreas suis, spleen (suis), proteus (morgani)· 1 maker
- agnus castus, ambra grisea, petroselinum sativum, estradiol, l-dopa, melatonin, testosterone, adenosinum triphosphoricum dinatrum, alpha-lipoicum acidum, nadidum, pantothenic acid, sarcolacticum acidum, ubidecarenonum, baryta carbonica, conium maculatum, selenium metallicum, folliculinum, funiculus umbilicalis suis, gaba, glandula suprarenalis suis, hepar suis, hypothalamus suis, lymph node (suis), medulla ossis suis, oophorinum (suis), orchitinum (suis), pancreas suis, spleen (suis), apiolum,· 1 maker
- agnus castus, angelica sin, apis mel, cimicifuga rac, estradiol, estriol, folliculinum, galium, glycyrrhiza, oophorinum, progesterone, sepia· 1 maker
- agnus castus, angelica sinensis, apis mellifica, arnica montana, cimicifuga racemosa, estradiol, estriol, folliculinum, galium aparine, glycyrrhiza glabra, korean ginseng, oophorinum (suis), progesterone, sepia, thuja occidentalis, viscum album· 1 maker
- allium cepa, galphimia glauca, sabadilla, apis mellifica, estradiol, kali sulphuricum, glandula suprarenalis (bovine), hepar (bovine), intestine (suis), stomach (suis), hypothalamus suis, lymph node (suis), ambrosia artemisiaefolia, carbo vegetabilis, peanut, black walnut, english walnut, amygdala amara, cashew, coconut, pecan, brazil nut, tomato, solanum tuberosum, piper nigrum, eggplant, rape seed oil, linum usitatissimum, sesame seed, cheese (stilton), lac vaccinum, beef, lamb, pork, chicken, egg,· 1 maker
- alpha-ketoglutaricum acidum, isoleucine, l-arginine, l carnitine, l-leucine, l-ornithine, l-valine, estradiol, folliculinum, progesterone, testosterone, oophorinum (suis)· 1 maker
- arsenic trioxide - estradiol - goldenseal - lachesis muta venom - magnesium phosphate - matricaria recutita - melatonin - progesterone - strychnos nux-vomica seed - sulfur - sus scrofa ovary - sus scrofa pituitary gland -· 1 maker
- dehydroepiandrosterone (dhea), estradiol, hypophysis suis, pregnenolone, progesterone, spleen (bovine), testosterone, thymus (suis), thyroidinum (suis)· 1 maker
- dehydroepiandrosterone, estradiol, pregnenolone, progesterone, testosterone· 1 maker
- dhea,adrenal cortisol,glandula suprarenalis suis,human growth hormone,igf-i,igf-ii ,hypothalamus,pituitary,placenta,liver,thymus,rna,dna,estrogenium,estradiolinum,sanguinara candensis,oophorinum,progesteronium,pitituarinum,pineal,folliculinum,ovarinum,cheladonium,sulphur,sepia,lagenine ,testosterone,cimicifuga black cohosh,lilium tigrinum,graphites,kali phosphoricum ,causticum,calcarea carbonica,phytolacca,scrophularia nodosa· 1 maker
Common questions
- Is Estradiol cypionate in shortage right now?
- No. FDA does not currently list Estradiol cypionate in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Estradiol cypionate?
- 11 companies have marketed Estradiol cypionate in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Estradiol cypionate cost?
- The typical pharmacy pays about $51.91 per mL, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.