The short version
4 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $2.33 per mL over the past year. It is in shortage right now — FDA lists the reason as “demand increase for the drug”.
Market view
morphine sulfate · Injection
11 marketed package NDCs · 4 active manufacturers
Most dispensed: 15 mg · Tablet · #100 tablets/bottle · 30 mg · Tablet · #100 tablets/bottle · 30 mg · Tablet, Film Coated, Extended Release · #100 tablet, film coated, extended releases/bottle · 15 mg · Tablet, Film Coated, Extended Release · #100 tablet, film coated, extended releases/bottle, plastic
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $2.33 · middle half $2.32–$2.34 · full range $2.31–$2.34 · 2 products · 4 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for morphine sulfate, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Morphine SulfateSep 3, 2026New shortageby this manufacturerHospira, Inc., a Pfizer Company's Morphine Sulfate (Injection, 2 mg/1 mL) is newly in shortage — other37 companies market morphine sulfate · 5 have products in shortage
- Morphine SulfateAug 26, 2026Price upNADAC $0.21345 → $0.22817 per unit (+6.9%)
- Morphine SulfateAug 19, 2026Price downNADAC $0.48576 → $0.47957 per unit (-1.27%)
- Morphine SulfateAug 19, 2026Price downNADAC $0.32278 → $0.31825 per unit (-1.4%)
- Morphine SulfateAug 19, 2026Price downNADAC $0.41876 → $0.40963 per unit (-2.18%)
- Morphine SulfateAug 19, 2026Price downNADAC $0.12011 → $0.12007 per unit (-0.03%)
- Morphine SulfateAug 19, 2026Price downNADAC $0.04449 → $0.0438 per unit (-1.55%)
- Morphine SulfateAug 19, 2026Price upNADAC $0.08944 → $0.09072 per unit (+1.43%)
- Morphine Sulfate Extended ReleaseAug 19, 2026Price upNADAC $0.43337 → $0.45546 per unit (+5.1%)
- Morphine Sulfate Extended ReleaseAug 19, 2026Price downNADAC $0.31815 → $0.31296 per unit (-1.63%)
Same drug class
Other molecules FDA puts in Opioid Agonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- morphine· in shortage
- fentanyl· in shortage
- remifentanil hydrochloride· in shortage
- sufentanil citrate· in shortage
- meperidine hydrochloride· in shortage
- fentanyl citrate· in shortage
- hydromorphone hydrochloride· in shortage
- acetaminophen, caffeine, dihydrocodeine bitartrate· 1 maker
- butalbital, aspirin, cafeine, and codeine phosphate· 1 maker
- codeine phosphate and chlorpheniramine maleate· 1 maker
- codeine phosphate, dexbrompheniramine maleate· 1 maker
- fentanyl transdermal· 1 maker
Common questions
- Is Morphine sulfate in shortage right now?
- Yes. FDA currently lists Morphine sulfate in shortage. This page is rebuilt every morning from FDA's shortage database.
- Who makes Morphine sulfate?
- 37 companies have marketed Morphine sulfate in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Morphine sulfate cost?
- The typical pharmacy pays about $0.4096 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
Shortage reports for this molecule
- In shortage now — Morphine Sulfate, Injection, 1 mg/1 mL (NDC 76329-1912-1)Dec 6, 2018
- In shortage now — Duramorph, Injection, .5 mg/1 mL (NDC 0641-6020-10)Nov 3, 2017
- In shortage now — Duramorph, Injection, 1 mg/1 mL (NDC 0641-6019-10)Nov 3, 2017
- In shortage now — Morphine Sulfate, Injection, 10 mg/1 mL (NDC 0641-6127-25)Nov 3, 2017
- In shortage now — Morphine Sulfate, Injection, 4 mg/1 mL (NDC 0641-6125-25)Nov 3, 2017
- In shortage now — Morphine Sulfate, Injection, 8 mg/1 mL (NDC 0641-6126-25)Nov 3, 2017
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.