The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
Market view
acetaminophen, guaifenesin, phenylephrine hcl · Liquid
3 marketed package NDCs · 3 active manufacturers
Most dispensed: 325 mg; 200 mg; PHENYLEPHRINE HYDROCHLORIDE 5 mg · Tablet, Film Coated · #2 blister packs/carton / 12 tablet, film coated in 1 blister pack · 325 mg; 200 mg; PHENYLEPHRINE HYDROCHLORIDE 5 mg · Tablet, Film Coated · #2 blister packs/carton / 10 tablet, film coated in 1 blister pack
What changed in the last 90 days
Every detected change for acetaminophen, guaifenesin, phenylephrine hcl, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Sinus SevereAug 19, 2026Price downNADAC $0.10738 → $0.10471 per unit (-2.49%)
- Head Congestion and MucusAug 19, 2026Price downNADAC $0.10738 → $0.10471 per unit (-2.49%)
- Sinus SevereJul 22, 2026Price downNADAC $0.10823 → $0.10738 per unit (-0.79%)
- Head Congestion and MucusJul 22, 2026Price downNADAC $0.10823 → $0.10738 per unit (-0.79%)
Same drug class
Other molecules FDA puts in Expectorant, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- acetaminophen 650 mg, dextromethorphan hbr 20 mg, guaifenesin 400 mg, phenylephrine hcl 10 mg· 1 maker
- acetaminophen dextromethorphan hbr guaifenesin, phenylephrine hcl· 1 maker
- acetaminophen guaifenesein phenylephrine hcl· 1 maker
- acetaminophen-chlorpheniramine maleate-dextromethorphan hbr-guaifenesin-phenylephrine hcl· 1 maker
- acetaminophen-phenylephrine hcl-guaifenesin· 1 maker
- acetaminophen, dextromethophan hbr, phenylephrine hcl, guaifenesin· 1 maker
- acetaminophen, dextromethorphan hbr, guafeisin usp, phenylephrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin usp, phenylephrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl tablet· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl tablet, film coated tablet· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, guailfenesin,phenlyephrine hcl· 1 maker
Common questions
- Is Acetaminophen, guaifenesin, phenylephrine hcl in shortage right now?
- No. FDA does not currently list Acetaminophen, guaifenesin, phenylephrine hcl in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Acetaminophen, guaifenesin, phenylephrine hcl?
- 19 companies have marketed Acetaminophen, guaifenesin, phenylephrine hcl in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Acetaminophen, guaifenesin, phenylephrine hcl cost?
- The typical pharmacy pays about $0.1047 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.