The short version
Only one company currently supplies this market — there is no backup if it stumbles.
Market view
bupivacaine hydrochloride · Liquid
1 marketed package NDCs · 1 active manufacturer
Most dispensed: 5 mg/mL · Injection, Solution · #1 vial/carton / 50 ml in 1 vial · 5 mg/mL · Injection, Solution · #50 mL/vial, multi-dose · 2.5 mg/mL · Injection, Solution · #1 vial/carton / 50 ml in 1 vial · 2.5 mg/mL · Injection, Solution · #1 vial, multi-dose/carton / 50 ml in 1 vial, multi-dose
What changed in the last 90 days
Every detected change for bupivacaine hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- MarcaineSep 3, 2026New shortageby this manufacturerHospira, Inc., a Pfizer Company's Marcaine (Injection, 250 mg/50 mL) is newly in shortage35 companies market marcaine · 8 have products in shortage
- MarcaineSep 3, 2026New shortageby this manufacturerHospira, Inc., a Pfizer Company's Marcaine (Injection, 225 mg/30 mL) is newly in shortage35 companies market marcaine · 8 have products in shortage
- bupivacaine hydrochlorideSep 3, 2026Now in shortageby this manufacturerKindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 28, 2026Being discontinuedby this manufacturerKindos Pharmaceuticals Co. Ltd. plans to stop making its bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) — was in shortage35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 27, 2026Now in shortageby this manufacturerKindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 27, 2026Being discontinuedby this manufacturerKindos Pharmaceuticals Co. Ltd. plans to stop making its bupivacaine hydrochloride (Injection, 5 mg/1 mL) — was in shortage35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 23, 2026Now in shortageby this manufacturerKindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 23, 2026Being discontinuedby this manufacturerKindos Pharmaceuticals Co. Ltd. plans to stop making its bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) — was in shortage35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 22, 2026Now in shortageby this manufacturerKindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
- bupivacaine hydrochlorideAug 22, 2026Now in shortageby this manufacturerKindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
Same drug class
Other molecules FDA puts in Amide Local Anesthetic, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- bupivacaine hydrochloride in dextrose· in shortage
- bupivacaine hydrochloride and epinephrine· in shortage
- lidocaine hydrochloride anhydrous and dextrose monohydrate· in shortage
- lidocaine hydrochloride anhydrous· in shortage
- bupivacaine hydrochloride and epinephrine bitartrate· in shortage
- lidocaine hydrochloride,epinephrine bitartrate· in shortage
- lidocaine hydrochloride and epinephrine· in shortage
- bupivacaine· in shortage
- ropivacaine hydrochloride· in shortage
- lidocaine hydrochloride· in shortage
- lidocaine· in shortage
- 0.25% bupivacaine hcl· 1 maker
Common questions
- Is Bupivacaine hydrochloride in shortage right now?
- Yes. FDA currently lists Bupivacaine hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database.
- Who makes Bupivacaine hydrochloride?
- 35 companies have marketed Bupivacaine hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Bupivacaine hydrochloride cost?
- The typical pharmacy pays about $0.0669 per mL, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.