The short version
Only one company currently supplies this market — there is no backup if it stumbles. The price has held steady around $2.42 per gram over the past year.
Market view
tretinoin · Lotion
5 marketed package NDCs · 1 active manufacturer
Most dispensed: .25 mg/g · Cream · #1 tube/carton / 20 g in 1 tube · .25 mg/g · Cream · #1 tube/carton / 45 g in 1 tube · 1 mg/g · Cream · #1 tube/carton / 20 g in 1 tube · 1 mg/g · Cream · #1 tube/carton / 45 g in 1 tube
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Mar 2026 — typical price $2.42 · middle half $2.41–$2.44 · full range $2.39–$2.45 · 2 products · 1 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for tretinoin, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- TretinoinAug 19, 2026Price upNADAC $0.94209 → $0.95747 per unit (+1.63%)
- TretinoinAug 19, 2026Price downNADAC $0.79113 → $0.7625 per unit (-3.62%)
- TretinoinAug 19, 2026Price downNADAC $8.76036 → $8.53098 per unit (-2.62%)
- Tretinoin (Microsphere)Aug 19, 2026Price upNADAC $10.59353 → $11.6297 per unit (+9.78%)
- TretinoinAug 19, 2026Price downNADAC $8.76036 → $8.53098 per unit (-2.62%)
- TretinoinAug 19, 2026Price downNADAC $0.47614 → $0.46837 per unit (-1.63%)
- TretinoinAug 19, 2026Price downNADAC $0.56151 → $0.55354 per unit (-1.42%)
- TretinoinAug 19, 2026Price downNADAC $0.79113 → $0.7625 per unit (-3.62%)
- TretinoinAug 19, 2026Price upNADAC $0.94209 → $0.95747 per unit (+1.63%)
- TretinoinAug 19, 2026Price upNADAC $2.69913 → $2.70733 per unit (+0.3%)
Same drug class
Other molecules FDA puts in Retinoid, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- adaplaene· 1 maker
- adaplane 0.1%· 1 maker
- benzoyl peroxide and tretinoin· 1 maker
- clindamycin phosphate and tretinoin gel 1.2%/0.025%· 1 maker
- clindamycin phosphate/benzoyl peroxide/adapalene· 1 maker
- fluocinolone acetonide, hydroquinone, and tretinoin· 1 maker
- halobetasol propionate and tazarotene· 1 maker
- tretinoin and benzoyl peroxide· 1 maker
- adapalene and benzoyl peroxide gel, 0.1%/2.5%· 2 makers
- adapalene and benzoyl peroxide topical· 2 makers
- adapalene gel usp, 0.3%· 2 makers
- acne treatment· 3 makers
Common questions
- Is Tretinoin in shortage right now?
- No. FDA does not currently list Tretinoin in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Tretinoin?
- 45 companies have marketed Tretinoin in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Tretinoin cost?
- The typical pharmacy pays about $0.9575 per gram, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.