The short version
18 companies supply this market — deep enough that no single failure threatens the supply.
Market view
apremilast · Powder
33 marketed package NDCs · 18 active manufacturers
Most dispensed: Kit · #1 blister pack/carton / 1 kit in 1 blister pack · 75 mg · Tablet, Film Coated · #30 tablet, film coateds/bottle · 20 mg · Tablet, Film Coated · #60 tablet, film coateds/bottle · 30 mg · Tablet, Film Coated · #60 tablet, film coateds/bottle
What changed in the last 90 days
Every detected change for apremilast, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- OtezlaAug 19, 2026Price upNADAC $180.628 → $181.01929 per unit (+0.22%)
- OtezlaAug 19, 2026Price downNADAC $98.70095 → $98.55082 per unit (-0.15%)
- OtezlaAug 19, 2026Price downNADAC $90.55699 → $90.54823 per unit (-0.01%)
- ApremilastAug 18, 2026Mfr enteredLee Pharma Ltd. · apremilast
- ApremilastAug 18, 2026New productLee Pharma Ltd.
- ApremilastAug 18, 2026New productLee Pharma Ltd.
- ApremilastAug 18, 2026New productLee Pharma Ltd.
- ApremilastAug 18, 2026New productLee Pharma Ltd.
- ApremilastAug 18, 2026New productLee Pharma Ltd.
- OtezlaAug 12, 2026Product updateapplication number: NDA205437 → NDA210745
Same drug class
Other molecules FDA puts in Phosphodiesterase 4 Inhibitor, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
Common questions
- Is Apremilast in shortage right now?
- No. FDA does not currently list Apremilast in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Apremilast?
- 20 companies have marketed Apremilast in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Apremilast cost?
- The typical pharmacy pays about $98.55 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.