The short version
15 companies supply this market — deep enough that no single failure threatens the supply.
Market view
buprenorphine · Powder
25 marketed package NDCs · 15 active manufacturers
Most dispensed: HYDROCHLORIDE 8 mg · Tablet · #30 tablets/bottle · HYDROCHLORIDE 2 mg · Tablet · #30 tablets/bottle · 7.5 ug/h · Patch, Extended Release · #4 pouchs/carton / 1 patch in 1 pouch / 168 h in 1 patch · 15 ug/h · Patch, Extended Release · #4 pouchs/carton / 1 patch in 1 pouch / 168 h in 1 patch
What changed in the last 90 days
Every detected change for buprenorphine, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- BuprenorphineAug 19, 2026Price upNADAC $35.6137 → $37.85016 per unit (+6.28%)
- BuprenorphineAug 19, 2026Price upNADAC $54.2378 → $57.31739 per unit (+5.68%)
- BuprenorphineAug 19, 2026Price upNADAC $50.15984 → $52.6954 per unit (+5.05%)
- BuprenorphineAug 19, 2026Price upNADAC $31.32023 → $33.75264 per unit (+7.77%)
- BuprenorphineAug 19, 2026Price upNADAC $22.92249 → $23.81869 per unit (+3.91%)
- BuprenorphineAug 19, 2026Price upNADAC $0.5618 → $0.56762 per unit (+1.04%)
- BuprenorphineAug 19, 2026Price downNADAC $0.27156 → $0.26477 per unit (-2.5%)
- BuprenorphineAug 19, 2026Price upNADAC $0.5618 → $0.56762 per unit (+1.04%)
- BuprenorphineAug 19, 2026Price downNADAC $0.27156 → $0.26477 per unit (-2.5%)
- ButransAug 19, 2026Price upNADAC $124.59981 → $124.6134 per unit (+0.01%)
Same drug class
Other molecules FDA puts in Partial Opioid Agonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- buprenorphine hydrochloride, naloxone hydrochloride· 1 maker
- buprenorphine sublingual· 1 maker
- buprenorphine sublingual c-iii· 1 maker
- buprenorphine hydrochloride and naloxone hydrochloride· 4 makers
- buprenorphine hcl· 10 makers
- buprenorphine hydrochloride and naloxone hydrochloride dihydrate· 10 makers
- buprenorphine and naloxone· 19 makers
- buprenorphine hydrochloride· 29 makers
Common questions
- Is Buprenorphine in shortage right now?
- No. FDA does not currently list Buprenorphine in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Buprenorphine?
- 37 companies have marketed Buprenorphine in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Buprenorphine cost?
- The typical pharmacy pays about $33.75 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.