The short version
5 companies supply this market — a reasonable cushion if one runs into trouble.
Market view
esketamine hydrochloride · Powder
9 marketed package NDCs · 5 active manufacturers
Most dispensed: 28 mg/.2mL · Solution · #2 blister packs/kit / 1 vial, single-use in 1 blister pack / .2 ml in 1 vial, single-use · 28 mg/.2mL · Solution · #3 blister packs/kit / 1 vial, single-use in 1 blister pack / .2 ml in 1 vial, single-use
What changed in the last 90 days
Every detected change for esketamine hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- SpravatoAug 27, 2026Mfr enteredJanssen Pharmaceuticals, Inc. · esketamine hydrochloride
- SpravatoAug 27, 2026Product updatelabeler name: Janssen Pharmaceuticals Inc. → Janssen Pharmaceuticals, Inc.
- SpravatoAug 27, 2026Product updatelabeler name: Janssen Pharmaceuticals Inc. → Janssen Pharmaceuticals, Inc.
- SpravatoAug 19, 2026Price downNADAC $431.77428 → $431.22778 per unit (-0.13%)
- SpravatoJul 22, 2026Price upNADAC $429.4325 → $431.77428 per unit (+0.55%)
Common questions
- Is Esketamine hydrochloride in shortage right now?
- No. FDA does not currently list Esketamine hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Esketamine hydrochloride?
- 7 companies have marketed Esketamine hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Esketamine hydrochloride cost?
- The typical pharmacy pays about $431.23 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.