The short version
9 companies supply this market — a reasonable cushion if one runs into trouble.
Market view
hydroxyurea · Powder
21 marketed package NDCs · 9 active manufacturers
Most dispensed: 500 mg · Capsule · #100 capsules/bottle · 500 mg · Capsule · #100 capsules/bottle, plastic · 300 mg · Capsule · #60 capsules/bottle · 200 mg · Capsule · #60 capsules/bottle
What changed in the last 90 days
Every detected change for hydroxyurea, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- SiklosAug 19, 2026Price upNADAC $6.2149 → $6.22986 per unit (+0.24%)
- HydroxyureaAug 19, 2026Price downNADAC $0.19019 → $0.18676 per unit (-1.8%)
- HydroxyureaAug 19, 2026Price downNADAC $0.19019 → $0.18676 per unit (-1.8%)
- HydroxyureaAug 19, 2026Price downNADAC $0.19019 → $0.18676 per unit (-1.8%)
- XromiAug 19, 2026Price upNADAC $4.95679 → $4.95684 per unit (0%)
- HydroxyureaAug 19, 2026Price downNADAC $0.19019 → $0.18676 per unit (-1.8%)
- HydroxyureaAug 19, 2026Price downNADAC $0.19019 → $0.18676 per unit (-1.8%)
- HydroxyureaAug 19, 2026Price downNADAC $0.19019 → $0.18676 per unit (-1.8%)
- HydroxyureaJul 22, 2026Price downNADAC $0.19098 → $0.19019 per unit (-0.41%)
- HydroxyureaJul 22, 2026Price downNADAC $0.19098 → $0.19019 per unit (-0.41%)
Same drug class
Other molecules FDA puts in Antimetabolite, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
Common questions
- Is Hydroxyurea in shortage right now?
- No. FDA does not currently list Hydroxyurea in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Hydroxyurea?
- 23 companies have marketed Hydroxyurea in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Hydroxyurea cost?
- The typical pharmacy pays about $0.1868 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.