The short version
6 companies supply this market — a reasonable cushion if one runs into trouble.
Market view
lubiprostone · Powder
14 marketed package NDCs · 6 active manufacturers
Most dispensed: 24 ug · Capsule, Gelatin Coated · #60 capsule, gelatin coateds/bottle · 8 ug · Capsule, Gelatin Coated · #60 capsule, gelatin coateds/bottle · .024 mg · Capsule · #60 capsules/bottle · .008 mg · Capsule · #60 capsules/bottle
What changed in the last 90 days
Every detected change for lubiprostone, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- LubiprostoneAug 19, 2026Price downNADAC $0.63045 → $0.62385 per unit (-1.05%)
- LubiprostoneAug 19, 2026Price downNADAC $0.55634 → $0.5493 per unit (-1.27%)
- LubiprostoneAug 19, 2026Price downNADAC $0.63045 → $0.62385 per unit (-1.05%)
- LubiprostoneAug 19, 2026Price downNADAC $0.55634 → $0.5493 per unit (-1.27%)
- LubiprostoneAug 19, 2026Price downNADAC $0.63045 → $0.62385 per unit (-1.05%)
- LubiprostoneAug 19, 2026Price downNADAC $0.55634 → $0.5493 per unit (-1.27%)
- LubiprostoneAug 19, 2026Price downNADAC $0.63045 → $0.62385 per unit (-1.05%)
- LubiprostoneAug 19, 2026Price downNADAC $0.55634 → $0.5493 per unit (-1.27%)
- LubiprostoneAug 19, 2026Price downNADAC $0.63045 → $0.62385 per unit (-1.05%)
- LubiprostoneAug 19, 2026Price downNADAC $0.55634 → $0.5493 per unit (-1.27%)
Common questions
- Is Lubiprostone in shortage right now?
- No. FDA does not currently list Lubiprostone in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Lubiprostone?
- 27 companies have marketed Lubiprostone in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Lubiprostone cost?
- The typical pharmacy pays about $0.6239 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.