The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
Market view
misoprostol · Powder
9 marketed package NDCs · 3 active manufacturers
Most dispensed: 200 ug · Tablet · #60 tablets/bottle · 200 ug · Tablet · #100 tablets/bottle · 100 ug · Tablet · #120 tablets/bottle · 100 ug · Tablet · #60 tablets/bottle
What changed in the last 90 days
Every detected change for misoprostol, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- MisoprostolAug 19, 2026Price downNADAC $0.74142 → $0.73379 per unit (-1.03%)
- MisoprostolAug 19, 2026Price downNADAC $0.74142 → $0.73379 per unit (-1.03%)
- MisoprostolAug 19, 2026Price upNADAC $0.47594 → $0.48163 per unit (+1.2%)
- MisoprostolAug 19, 2026Price upNADAC $0.47594 → $0.48163 per unit (+1.2%)
- MisoprostolAug 19, 2026Price downNADAC $0.74142 → $0.73379 per unit (-1.03%)
- MisoprostolAug 19, 2026Price upNADAC $0.47594 → $0.48163 per unit (+1.2%)
- misoprostolAug 19, 2026Price downNADAC $0.74142 → $0.73379 per unit (-1.03%)
- misoprostolAug 19, 2026Price downNADAC $0.74142 → $0.73379 per unit (-1.03%)
- misoprostolAug 19, 2026Price upNADAC $0.47594 → $0.48163 per unit (+1.2%)
- misoprostolAug 19, 2026Price upNADAC $0.47594 → $0.48163 per unit (+1.2%)
Same drug class
Other molecules FDA puts in Prostaglandin E1 Analog, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
Common questions
- Is Misoprostol in shortage right now?
- No. FDA does not currently list Misoprostol in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Misoprostol?
- 23 companies have marketed Misoprostol in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Misoprostol cost?
- The typical pharmacy pays about $0.7338 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.