The short version
22 companies supply this market — deep enough that no single failure threatens the supply.
Market view
naltrexone hydrochloride · Powder
80 marketed package NDCs · 22 active manufacturers
Most dispensed: 50 mg · Tablet, Film Coated · #30 tablet, film coateds/bottle · 50 mg · Tablet, Film Coated · #100 tablet, film coateds/bottle · 50 mg · Tablet, Film Coated · #60 tablet, film coateds/bottle · 50 mg · Tablet, Film Coated · #90 tablet, film coateds/bottle
What changed in the last 90 days
Every detected change for naltrexone hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
- Naltrexone HydrochlorideAug 19, 2026Price downNADAC $1.16038 → $1.13919 per unit (-1.83%)
Same drug class
Other molecules FDA puts in Opioid Antagonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- buprenorphine hydrochloride, naloxone hydrochloride· 1 maker
- naldemedine· 1 maker
- nalmefene hydrochloride injection· 1 maker
- naloxone hci· 1 maker
- naltrexone hydrochloride and bupropion hydrochloride· 1 maker
- narcan naloxone hci· 1 maker
- narcan naloxone hcl· 1 maker
- olanzapine and samidorphan l-malate· 1 maker
- pentazocine and naloxone· 1 maker
- naloxone· 2 makers
- pentazocine hydrochloride and naloxone hydrochloride· 2 makers
- naloxone hydrochloride nasal· 3 makers
Common questions
- Is Naltrexone hydrochloride in shortage right now?
- No. FDA does not currently list Naltrexone hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Naltrexone hydrochloride?
- 42 companies have marketed Naltrexone hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Naltrexone hydrochloride cost?
- The typical pharmacy pays about $1.14 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.