The short version
Only one company currently supplies this market — there is no backup if it stumbles. The price has held steady around $126.10 per gram over the past year.
Market view
tiotropium bromide inhalation spray · Spray, Metered
5 marketed package NDCs · 1 active manufacturer
Most dispensed: TIOTROPIUM BROMIDE ANHYDROUS 3.124 ug · Spray, Metered · #1 cartridge/carton / 60 spray, metered in 1 cartridge · TIOTROPIUM BROMIDE ANHYDROUS 1.562 ug · Spray, Metered · #1 cartridge/carton / 60 spray, metered in 1 cartridge
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $126.10 · middle half $126.09–$126.11 · full range $126.07–$126.12 · 2 products · 1 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for tiotropium bromide inhalation spray, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Spiriva RespimatAug 19, 2026Price downNADAC $126.08688 → $126.07392 per unit (-0.01%)
- Spiriva RespimatAug 19, 2026Price upNADAC $126.12498 → $126.11976 per unit (0%)
- Spiriva RespimatJul 22, 2026Price downNADAC $126.15984 → $126.12498 per unit (-0.03%)
- Spiriva RespimatJul 22, 2026Price upNADAC $126.0828 → $126.08688 per unit (0%)
Same drug class
Other molecules FDA puts in Anticholinergic, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- atropine sulfate injection· in shortage
- atropine sulfate monohydrate· in shortage
- atropine· in shortage
- atropine sulfate· in shortage
- aclidinium bromide and formoterol fumarate· 1 maker
- aconitum napellus, adrenalinum, agaricus muscarius, apis mellifica, atropinum, camphora, cantharis, causticum, cerebrum suis, chamomilla, cicuta virosa, cuprum metallicum, homarus, hyoscyamus niger, hypophysis suis, lac caninum, moschus, stramonium, tarentula hispana, veratrum album· 1 maker
- adrenal drops· 1 maker
- ammi vis, atropinum sulphuricum, boldo, carduus mar, chelidonium maj, echinacea, fel tauri, hepar suis, hydrastis, leptandra, mag phos, nat phos, podoph pelt, taraxacum· 1 maker
- ammi visnaga, atropinum sulphuricum, boldo, carduus marianus, chelidonium majus, echinacea, fel tauri, hepar suis, hydrastis canadensis, leptandra virginica, magnesia phosphorica, natrum phosphoricum, podophyllum peltatum, taraxacum officinale· 1 maker
- apis mellifica, cantharis, chamomilla, adrenalinum, cerebrum suis, hypophysis suis, aconitum napellus, agaricus muscarius, atropinum, causticum, cicuta virosa, cuprum metallicum, hyoscyamus niger, lac caninum, moschus, stramonium, tarentula hispana, veratrum album, homarus, camphora· 1 maker
- arg nitd3, atropin sulphd6, bufo rand10, cuprum aceticd3, oenanthe crocd5, zinc valeriand2· 1 maker
- argentum metallicum, artemisia vulgaris, cicuta virosa, cobaltum metallicum, cocculus indicus, conium maculatum, ginkgo biloba, kali bromatum, lathyrus sativus, mercurius solubilis, nux vomica, plumbum metallicum, salix alba, scopolaminum hydrobromidum, sequoiadendron giganteum, sus scrofa cerebrum· 1 maker
Common questions
- Is Tiotropium bromide inhalation spray in shortage right now?
- No. FDA does not currently list Tiotropium bromide inhalation spray in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Tiotropium bromide inhalation spray?
- 1 company has marketed Tiotropium bromide inhalation spray in the last 30 days, according to the FDA NDC Directory. That is a thin market — if one stops making it, supply is at risk quickly. Every manufacturer and package is listed on this page.
- What does Tiotropium bromide inhalation spray cost?
- The typical pharmacy pays about $126.10 per gram, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.