The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
Market view
hydromorphone hydrochloride · Suppository
2 marketed package NDCs · 2 active manufacturers
Most dispensed: 16 mg · Tablet, Extended Release · #100 tablet, extended releases/bottle · 12 mg · Tablet, Extended Release · #100 tablet, extended releases/bottle · 8 mg · Tablet, Extended Release · #100 tablet, extended releases/bottle · 4 mg · Tablet · #100 tablets/bottle, plastic
What changed in the last 90 days
Every detected change for hydromorphone hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Hydromorphone HydrochlorideAug 27, 2026Mfr enteredRedpharm Drug · hydromorphone hydrochloride
- Hydromorphone HydrochlorideAug 27, 2026New productRedpharm Drug
- Hydromorphone HydrochlorideAug 19, 2026Price downNADAC $0.21942 → $0.21677 per unit (-1.21%)
- Hydromorphone HydrochlorideAug 19, 2026Price upNADAC $0.16585 → $0.16713 per unit (+0.77%)
- Hydromorphone HydrochlorideAug 19, 2026Price downNADAC $0.23793 → $0.23639 per unit (-0.65%)
- Hydromorphone HydrochlorideAug 19, 2026Price upNADAC $0.5677 → $0.56832 per unit (+0.11%)
- Hydromorphone HydrochlorideAug 19, 2026Price downNADAC $0.21942 → $0.21677 per unit (-1.21%)
- Hydromorphone HydrochlorideAug 19, 2026Price downNADAC $0.21942 → $0.21677 per unit (-1.21%)
- Hydromorphone HydrochlorideAug 19, 2026Price downNADAC $0.21942 → $0.21677 per unit (-1.21%)
- Hydromorphone HydrochlorideAug 19, 2026Price upNADAC $0.16585 → $0.16713 per unit (+0.77%)
Same drug class
Other molecules FDA puts in Opioid Agonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- morphine· in shortage
- fentanyl· in shortage
- remifentanil hydrochloride· in shortage
- sufentanil citrate· in shortage
- meperidine hydrochloride· in shortage
- fentanyl citrate· in shortage
- morphine sulfate· in shortage
- acetaminophen, caffeine, dihydrocodeine bitartrate· 1 maker
- butalbital, aspirin, cafeine, and codeine phosphate· 1 maker
- codeine phosphate and chlorpheniramine maleate· 1 maker
- codeine phosphate, dexbrompheniramine maleate· 1 maker
- fentanyl transdermal· 1 maker
Common questions
- Is Hydromorphone hydrochloride in shortage right now?
- Yes. FDA currently lists Hydromorphone hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database.
- Who makes Hydromorphone hydrochloride?
- 29 companies have marketed Hydromorphone hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Hydromorphone hydrochloride cost?
- The typical pharmacy pays about $2.57 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
Shortage reports for this molecule
- Planned discontinuation — Hydromorphone Hydrochloride, Suppository, 3 mg (NDC 0574-7224-06)Jul 23, 2026
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.