The short version
9 companies supply this market — a reasonable cushion if one runs into trouble.
Market view
acetaminophen, phenylephrine hcl · Tablet, Film Coated
11 marketed package NDCs · 9 active manufacturers
Most dispensed: 325 mg; PHENYLEPHRINE HYDROCHLORIDE 5 mg · Tablet · #2 blister packs/carton / 12 tablet in 1 blister pack · 325 mg; PHENYLEPHRINE HYDROCHLORIDE 5 mg · Tablet, Film Coated · #2 blister packs/carton / 12 tablet, film coated in 1 blister pack
What changed in the last 90 days
Every detected change for acetaminophen, phenylephrine hcl, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- McKesson Sinus Pain and Pressure ReliefSep 2, 2026Mfr exitedMcKesson Medical-Surgical · acetaminophen, phenylephrine hcl
- McKesson Sinus Pain and Pressure ReliefAug 26, 2026Mfr enteredMcKesson Medical-Surgical · acetaminophen, phenylephrine hcl
- Sinus Pressure and Pain Maximum StrengthAug 19, 2026Price upNADAC $0.08485 → $0.08509 per unit (+0.28%)
- Sinus Pressure Pain Maximum Strength, Non-DrowsyAug 19, 2026Price upNADAC $0.08485 → $0.08509 per unit (+0.28%)
- Sinus Congestion and Pain Maximum StrengthAug 19, 2026Price upNADAC $0.08485 → $0.08509 per unit (+0.28%)
- McKesson Sinus Pain and Pressure ReliefJul 29, 2026Mfr exitedMcKesson Medical-Surgical · acetaminophen, phenylephrine hcl
- Sinus Pressure and Pain Maximum StrengthJul 22, 2026Price upNADAC $0.08254 → $0.08485 per unit (+2.8%)
- Sinus Congestion and Pain Maximum StrengthJul 22, 2026Price upNADAC $0.08254 → $0.08485 per unit (+2.8%)
- Sinus Pressure Pain Maximum Strength, Non-DrowsyJul 22, 2026Price upNADAC $0.08254 → $0.08485 per unit (+2.8%)
- McKesson Sinus Pain and Pressure ReliefJul 22, 2026Mfr enteredMcKesson Medical-Surgical · acetaminophen, phenylephrine hcl
Same drug class
Other molecules FDA puts in alpha-1 Adrenergic Agonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- lidocaine· in shortage
- 14.4% glycerin, 0.25% phenylephrine hcl, 1% pramoxine hcl, 15% petrolatum· 1 maker
- acetaminophen , diphenhydramine hcl,phenylephrine hcl· 1 maker
- acetaminophen , diphenhydramine hydrochloride,phenylephrine hydrochloride· 1 maker
- acetaminophen 325 mg dextromethorphan hbr 10 mg phenylephrine hci 5 mg· 1 maker
- acetaminophen 325 mg, diphenhydramine hcl 12.5 mg, phenylephrine hcl 5 mg· 1 maker
- acetaminophen 650 mg, dextromethorphan hbr 20 mg, guaifenesin 400 mg, phenylephrine hcl 10 mg· 1 maker
- acetaminophen and phenyleprine hcl· 1 maker
- acetaminophen chlorpheniramine maleate dextromethorphan hydrobromide phenylepherine hydrochloride· 1 maker
- acetaminophen dextromethorphan hbr doxylamine succinate phenylephrine hci· 1 maker
- acetaminophen dextromethorphan hbr guaifenesin, phenylephrine hcl· 1 maker
- acetaminophen guaifenesein phenylephrine hcl· 1 maker
Common questions
- Is Acetaminophen, phenylephrine hcl in shortage right now?
- No. FDA does not currently list Acetaminophen, phenylephrine hcl in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Acetaminophen, phenylephrine hcl?
- 15 companies have marketed Acetaminophen, phenylephrine hcl in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Acetaminophen, phenylephrine hcl cost?
- The typical pharmacy pays about $0.0851 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.