Is Lorlatinib in shortage right now?

No. FDA does not currently list Lorlatinib in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.

Who makes Lorlatinib?

3 companies have marketed Lorlatinib in the last 30 days, according to the FDA NDC Directory. That is a thin market — if one stops making it, supply is at risk quickly. Every manufacturer and package is listed on this page.

Market view

lorlatinib · Tablet, Film Coated

6 marketed package NDCs · 3 active manufacturers

Most dispensed: 25 mg · Tablet, Film Coated · #30 tablet, film coateds/bottle

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately.

Same drug class

Other molecules FDA puts in Kinase Inhibitor, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.

Common questions

Is Lorlatinib in shortage right now?: No. FDA does not currently list Lorlatinib in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
Who makes Lorlatinib?: 3 companies have marketed Lorlatinib in the last 30 days, according to the FDA NDC Directory. That is a thin market — if one stops making it, supply is at risk quickly. Every manufacturer and package is listed on this page.

Shortage reports for this molecule

Planned discontinuation — Lorbrena, Tablet, 25 mg; 120 tablets bottle with a child-resistant closure (NDC 0069-0227-03)Jun 15, 2026

All marketed products

Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.