The short version
Only one company currently supplies this market — there is no backup if it stumbles. Historically, drugs in this position went on to a new shortage within 90 days about 0.3% of the time — roughly 2× the typical drug (0.1%).
Market view
desipramine hydrochloride · Tablet, Sugar Coated
6 marketed package NDCs · 1 active manufacturer
Most dispensed: 25 mg · Tablet, Film Coated · #100 tablet, film coateds/bottle · 10 mg · Tablet, Film Coated · #100 tablet, film coateds/bottle · 75 mg · Tablet, Film Coated · #100 tablet, film coateds/bottle · 100 mg · Tablet, Film Coated · #100 tablet, film coateds/bottle
What changed in the last 90 days
Every detected change for desipramine hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Desipramine HydrochlorideAug 19, 2026Price upNADAC $0.6292 → $0.83165 per unit (+32.18%)
- Desipramine HydrochlorideAug 19, 2026Price downNADAC $0.44812 → $0.44529 per unit (-0.63%)
- Desipramine HydrochlorideAug 19, 2026Price downNADAC $0.2798 → $0.27745 per unit (-0.84%)
- Desipramine HydrochlorideAug 19, 2026Price upNADAC $0.18693 → $0.2046 per unit (+9.45%)
- Desipramine HydrochlorideAug 19, 2026Price downNADAC $0.14695 → $0.14172 per unit (-3.56%)
- Desipramine HydrochlorideAug 19, 2026Price downNADAC $0.16487 → $0.15513 per unit (-5.91%)
- Desipramine HydrochlorideAug 19, 2026Price upNADAC $0.6292 → $0.83165 per unit (+32.18%)
- Desipramine HydrochlorideAug 19, 2026Price downNADAC $0.44812 → $0.44529 per unit (-0.63%)
- Desipramine HydrochlorideAug 19, 2026Price downNADAC $0.2798 → $0.27745 per unit (-0.84%)
- Desipramine HydrochlorideAug 19, 2026Price upNADAC $0.18693 → $0.2046 per unit (+9.45%)
Same drug class
Other molecules FDA puts in Tricyclic Antidepressant, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- clomipramine hydrochloride capsules· 1 maker
- desipramine· 1 maker
- doxepn hydrochloride· 1 maker
- nortriptyline hcl· 1 maker
- perphenazine and amitriptyline hydrochloride· 1 maker
- trimipramine· 1 maker
- chlordiazepoxide and amitriptyline hydrochloride· 2 makers
- desipramine hcl· 2 makers
- amoxapine· 3 makers
- doxepin hcl· 3 makers
- imipramine pamoate· 4 makers
- protriptyline hydrochloride· 4 makers
Common questions
- Is Desipramine hydrochloride in shortage right now?
- No. FDA does not currently list Desipramine hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Desipramine hydrochloride?
- 9 companies have marketed Desipramine hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Desipramine hydrochloride cost?
- The typical pharmacy pays about $0.2046 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.