The short version
28 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0848 per unit over the past year.
Market view
caffeine · Tablet
36 marketed package NDCs · 28 active manufacturers
Most dispensed: 200 mg · Tablet · #2 blister packs/carton / 8 tablet in 1 blister pack · 200 mg · Tablet · #5 blister packs/carton / 8 tablet in 1 blister pack · 1 g/108.27g · Chewable Gel · #108.27 g/bag · 1 kg/kg · Powder · #50 kg/drum
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $0.0848 · middle half $0.0848–$0.0848 · full range $0.0848–$0.0848 · 4 products · 28 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for caffeine, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Stay AwakeAug 19, 2026Price downNADAC $0.08489 → $0.0848 per unit (-0.11%)
- Stay AwakeAug 19, 2026Price downNADAC $0.08489 → $0.0848 per unit (-0.11%)
- CaffeineAug 19, 2026Price downNADAC $0.08489 → $0.0848 per unit (-0.11%)
- Alert AidAug 19, 2026Price downNADAC $0.08489 → $0.0848 per unit (-0.11%)
- Alertness AidAug 12, 2026Mfr exitedChain Drug Consortium · caffeine
- Stay AwakeJul 22, 2026Price upNADAC $0.08467 → $0.08489 per unit (+0.26%)
- CaffeineJul 22, 2026Price upNADAC $0.08467 → $0.08489 per unit (+0.26%)
- Alert AidJul 22, 2026Price upNADAC $0.08467 → $0.08489 per unit (+0.26%)
- Stay AwakeJul 22, 2026Price upNADAC $0.08467 → $0.08489 per unit (+0.26%)
Same drug class
Other molecules FDA puts in Methylxanthine, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- 5% minoxidil hair growth foam· 1 maker
- acetaldehyde, aceticum ac, arg nit, caffeinum, calc sulph, citricum ac, cortisone aceticum, echinacea purp, folliculinum, fragaria, fumaricum ac, gallicum ac, glandula suprarenalis suis, hepar suis, histaminum hydrochloricum, hydrangea, lac vac, lecithin, limulus, lycopersicum, lycopodium, nat bicarb, nat mur, nux vom, paraffinum, phosphoricum ac, saccharum off, silicea, tartaricum ac, torula cerevisiae.· 1 maker
- acetaminophen , aspirin and caffeine· 1 maker
- acetaminophen , caffeine and pyrilamine maleate· 1 maker
- acetaminophen 250 mg aspirin 250 mg caffeine 65 mg· 1 maker
- acetaminophen 250 mg, aspirin 250 mg, and caffeine 65 mg· 1 maker
- acetaminophen 250mg, aspirin 250mg and caffeine 65mg· 1 maker
- acetaminophen 500 mg with caffeine 65mg· 1 maker
- acetaminophen 500mg caffeine 60mg pyrilamine maleate 15mg· 1 maker
- acetaminophen 500mg pyrilamine maleate 15mg and caffeine 60mg tablets· 1 maker
- acetaminophen-aspirin-caffeine· 1 maker
- acetaminophen-caffeine· 1 maker
Common questions
- Is Caffeine in shortage right now?
- No. FDA does not currently list Caffeine in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Caffeine?
- 45 companies have marketed Caffeine in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Caffeine cost?
- The typical pharmacy pays about $0.0848 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.