The short version
Only one company currently supplies this market — there is no backup if it stumbles. The price has held steady around $0.9041 per unit over the past year.
Market view
acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl
2 marketed package NDCs · 1 active manufacturer
Most dispensed: PSEUDOEPHEDRINE HYDROCHLORIDE 60 mg; 325 mg; DEXTROMETHORPHAN HYDROBROMIDE 20 mg; 200 mg · Tablet · #100 tablets/bottle
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Apr 2026 — typical price $0.9041 · middle half $0.9041–$0.9041 · full range $0.9041–$0.9041 · 1 products · 1 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- DurafluSep 2, 2026Mfr exitedPoly Pharmaceuticals, Inc. · acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl
- DurafluAug 26, 2026Mfr enteredPoly Pharmaceuticals, Inc. · acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl
- DurafluJul 29, 2026Mfr exitedPoly Pharmaceuticals, Inc. · acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl
- DurafluJul 22, 2026Mfr enteredPoly Pharmaceuticals, Inc. · acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl
Same drug class
Other molecules FDA puts in alpha-Adrenergic Agonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- bupivacaine hydrochloride and epinephrine· in shortage
- bupivacaine hydrochloride and epinephrine bitartrate· in shortage
- lidocaine hydrochloride,epinephrine bitartrate· in shortage
- lidocaine hydrochloride and epinephrine· in shortage
- epinephrine· in shortage
- lidocaine hydrochloride· in shortage
- .alpha.-ketoglutaric acid - ambergris - anamirta cocculus seed - conium maculatum flowering top - epinephrine - fumaric acid - malic acid - melatonin - mineral oil - pteridium aquilinum root - pyridoxine hydrochloride - quinhydrone - quinine - sus scrofa artery - sus scrofa cerebellum - sus scrofa placenta - thiamine hydrochloride - tobacco leaf -· 1 maker
- acer negundo, acer rubrum, adrenalinum, allium cepa, arsenicum iodatum, betula nigra, euphrasia officinalis, fraxinus americana, histaminum hydrochloricum, ligustrum vulgare, liquidambar styraciflua, morus alba, pinus strobus, populus deltoides, quercus rubra, sabadilla, salix nigra, sanguinaria canadensis· 1 maker
- acetaminophen, chlorpheniramine maleate, dextromethorphan hbr, pseudoephedrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, pseudoephedrine hcl· 1 maker
- acetaminophen, pseudoephedrine· 1 maker
- aceticum ac, adrenalinum, adrenocorticotrophin (30x), aesculus hippocastanum, flos, alfalfa, alpha-lipoic ac, ambra, arg nit, avena sativa, bryonia, carboneum oxygenisatum, carpinus betulus, flos, dna, fumaricum acidum, gelsemium sempervirens, hepar sulphuris calcareum, hypothalamus, kali phosphoricum, lacticum acidum, lecithin, natrum muriaticum, oxalicum acidum, phosphoricum acidum, pituitarum posterium, sarcolacticum acidum, selenium metallicum, sepia, silicea, succinicum acidum and thyroidinum.· 1 maker
Common questions
- Is Acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl in shortage right now?
- No. FDA does not currently list Acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl?
- 1 company has marketed Acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl in the last 30 days, according to the FDA NDC Directory. That is a thin market — if one stops making it, supply is at risk quickly. Every manufacturer and package is listed on this page.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.