The short version
19 companies supply this market — deep enough that no single failure threatens the supply. The price is down 10% over the past year, to $0.1047 per unit.
Market view
acetaminophen, guaifenesin, phenylephrine hcl
30 marketed package NDCs · 19 active manufacturers
Most dispensed: 325 mg; 200 mg; PHENYLEPHRINE HYDROCHLORIDE 5 mg · Tablet, Film Coated · #2 blister packs/carton / 12 tablet, film coated in 1 blister pack · 325 mg; 200 mg; PHENYLEPHRINE HYDROCHLORIDE 5 mg · Tablet, Film Coated · #2 blister packs/carton / 10 tablet, film coated in 1 blister pack
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $0.1047 · middle half $0.1047–$0.1047 · full range $0.1047–$0.1047 · 2 products · 19 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for acetaminophen, guaifenesin, phenylephrine hcl, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Sinus SevereAug 19, 2026Price downNADAC $0.10738 → $0.10471 per unit (-2.49%)
- Head Congestion and MucusAug 19, 2026Price downNADAC $0.10738 → $0.10471 per unit (-2.49%)
- Sinus SevereJul 22, 2026Price downNADAC $0.10823 → $0.10738 per unit (-0.79%)
- Head Congestion and MucusJul 22, 2026Price downNADAC $0.10823 → $0.10738 per unit (-0.79%)
Same drug class
Other molecules FDA puts in Expectorant, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- acetaminophen 650 mg, dextromethorphan hbr 20 mg, guaifenesin 400 mg, phenylephrine hcl 10 mg· 1 maker
- acetaminophen dextromethorphan hbr guaifenesin, phenylephrine hcl· 1 maker
- acetaminophen guaifenesein phenylephrine hcl· 1 maker
- acetaminophen-chlorpheniramine maleate-dextromethorphan hbr-guaifenesin-phenylephrine hcl· 1 maker
- acetaminophen-phenylephrine hcl-guaifenesin· 1 maker
- acetaminophen, dextromethophan hbr, phenylephrine hcl, guaifenesin· 1 maker
- acetaminophen, dextromethorphan hbr, guafeisin usp, phenylephrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin usp, phenylephrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl tablet· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl tablet, film coated tablet· 1 maker
- acetaminophen, dextromethorphan hbr, guaifenesin, pseudoephedrine hcl· 1 maker
- acetaminophen, dextromethorphan hbr, guailfenesin,phenlyephrine hcl· 1 maker
Common questions
- Is Acetaminophen, guaifenesin, phenylephrine hcl in shortage right now?
- No. FDA does not currently list Acetaminophen, guaifenesin, phenylephrine hcl in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Acetaminophen, guaifenesin, phenylephrine hcl?
- 19 companies have marketed Acetaminophen, guaifenesin, phenylephrine hcl in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Acetaminophen, guaifenesin, phenylephrine hcl cost?
- The typical pharmacy pays about $0.1047 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.