DrugDashboards

Market view

bupivacaine hydrochloride

159 marketed package NDCs · 21 active manufacturers

Most dispensed: 5 mg/mL · Injection, Solution · #1 vial/carton / 50 ml in 1 vial · 5 mg/mL · Injection, Solution · #50 mL/vial, multi-dose · 2.5 mg/mL · Injection, Solution · #1 vial/carton / 50 ml in 1 vial · 2.5 mg/mL · Injection, Solution · #1 vial, multi-dose/carton / 50 ml in 1 vial, multi-dose

The short version

21 companies supply this market — deep enough that no single failure threatens the supply. The generic price is down 19% over the past year, to $0.0669 per mL. It is in shortage right now — FDA lists the reason as “discontinuation of the manufacture of the drug.

Price range and competition

RSS: changes for this drug
priced separately — they are not the same market

Generic products only. Every company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.

$0$0.05$0.1Nov 2024Sep 2026035companies actively selling

Latest · Sep 2026 — typical price $0.0669 · middle half $0.0479$0.086 · full range $0.0479$0.086 · 6 products · 35 companies

middle half of companies’ pricestypical (median) pricecompanies actively selling (bottom lane)Priced per mLSource: CMS NADAC
ⓘ How this was built
Data sources
  • CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
  • CMS Federal Upper Limit files (weighted AMP)
  • FDA NDC Directory (openFDA) — maker roster
Method

Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

What changed in the last 90 days

Every detected change for bupivacaine hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.

  • MarcaineSep 3, 2026
    New shortageby this manufacturer
    Hospira, Inc., a Pfizer Company's Marcaine (Injection, 250 mg/50 mL) is newly in shortage35 companies market marcaine · 8 have products in shortage
  • MarcaineSep 3, 2026
    New shortageby this manufacturer
    Hospira, Inc., a Pfizer Company's Marcaine (Injection, 225 mg/30 mL) is newly in shortage35 companies market marcaine · 8 have products in shortage
  • Now in shortageby this manufacturer
    Kindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Being discontinuedby this manufacturer
    Kindos Pharmaceuticals Co. Ltd. plans to stop making its bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) — was in shortage35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Now in shortageby this manufacturer
    Kindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Being discontinuedby this manufacturer
    Kindos Pharmaceuticals Co. Ltd. plans to stop making its bupivacaine hydrochloride (Injection, 5 mg/1 mL) — was in shortage35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Now in shortageby this manufacturer
    Kindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Being discontinuedby this manufacturer
    Kindos Pharmaceuticals Co. Ltd. plans to stop making its bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) — was in shortage35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Now in shortageby this manufacturer
    Kindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage
  • Now in shortageby this manufacturer
    Kindos Pharmaceuticals Co. Ltd.'s bupivacaine hydrochloride (Injection, 2.5 mg/1 mL) is now in shortage — was planned for discontinuation35 companies market bupivacaine hydrochloride · 8 have products in shortage

Same drug class

Other molecules FDA puts in Amide Local Anesthetic, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.

Common questions

Is Bupivacaine hydrochloride in shortage right now?
Yes. FDA currently lists Bupivacaine hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database.
Who makes Bupivacaine hydrochloride?
35 companies have marketed Bupivacaine hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
What does Bupivacaine hydrochloride cost?
The typical pharmacy pays about $0.0669 per mL, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.

Shortage reports for this molecule

  • In shortage nowBupivacaine Hydrochloride PRESERVATIVE FREE, Injection, 2.5 mg/1 mL (NDC 72266-263-10)Feb 20, 2018
  • In shortage nowBupivacaine Hydrochloride, Injection, 0.25%; 75 mg/30 mL (2.5 mg/mL) (NDC 0409-1159-10)Feb 20, 2018
  • In shortage nowBupivacaine Hydrochloride, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-1160-01)Feb 20, 2018
  • In shortage nowBupivacaine Hydrochloride, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1162-02)Feb 20, 2018
  • In shortage nowBupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-32)Feb 20, 2018
  • In shortage nowBupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-34)Feb 20, 2018

All marketed products

Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.