The short version
4 companies supply this market — a reasonable cushion if one runs into trouble. The brand price has held steady around $10.53 per unit over the past year. Generic versions run $0.5499 per unit — 19× cheaper.
Market view
buprenorphine hydrochloride and naloxone hydrochloride
14 marketed package NDCs · 4 active manufacturers
Most dispensed: 11.4 mg; 2.9 mg · Tablet, Orally Disintegrating · #3 blister packs/carton / 10 tablet, orally disintegrating in 1 blister pack · 1.4 mg; .36 mg · Tablet, Orally Disintegrating · #3 blister packs/carton / 10 tablet, orally disintegrating in 1 blister pack · 5.7 mg; 1.4 mg · Tablet, Orally Disintegrating · #3 blister packs/carton / 10 tablet, orally disintegrating in 1 blister pack · 8.6 mg; 2.1 mg · Tablet, Orally Disintegrating · #3 blister packs/carton / 10 tablet, orally disintegrating in 1 blister pack
Price range and competition
RSS: changes for this drugpriced separately — they are not the same market
Brand-name products only. Every company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $10.53 · middle half $5.26–$15.81 · full range $5.26–$21.05 · 12 products · 3 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for buprenorphine hydrochloride and naloxone hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Buprenorphine and NaloxoneAug 26, 2026Mfr exitedPAI Holdings, LLC dba Pharmaceutical Associates, Inc. and dba PAI Pharma · buprenorphine hydrochloride and naloxone hydrochloride
- Buprenorphine and NaloxoneAug 26, 2026Mfr exitedPAI Holdings, LLC dba Pharmaceutical Associates, Inc. and dba PAI Pharma · buprenorphine hydrochloride and naloxone hydrochloride
- ZubsolvAug 19, 2026Price downNADAC $21.055 → $21.05236 per unit (-0.01%)
- ZubsolvAug 19, 2026Price downNADAC $15.81759 → $15.81379 per unit (-0.02%)
- ZubsolvAug 19, 2026Price downNADAC $10.55032 → $10.54624 per unit (-0.04%)
- ZubsolvAug 19, 2026Price downNADAC $10.52801 → $10.5236 per unit (-0.04%)
- ZubsolvAug 19, 2026Price upNADAC $5.26081 → $5.26319 per unit (+0.05%)
- ZubsolvAug 19, 2026Price downNADAC $5.26518 → $5.26374 per unit (-0.03%)
- ZubsolvAug 19, 2026Price downNADAC $15.81759 → $15.81379 per unit (-0.02%)
- ZubsolvAug 19, 2026Price downNADAC $10.55032 → $10.54624 per unit (-0.04%)
Same drug class
Other molecules FDA puts in Partial Opioid Agonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- buprenorphine hydrochloride, naloxone hydrochloride· 1 maker
- buprenorphine sublingual· 1 maker
- buprenorphine sublingual c-iii· 1 maker
- buprenorphine hcl· 10 makers
- buprenorphine hydrochloride and naloxone hydrochloride dihydrate· 10 makers
- buprenorphine and naloxone· 19 makers
- buprenorphine hydrochloride· 29 makers
- buprenorphine· 37 makers
Common questions
- Is Buprenorphine hydrochloride and naloxone hydrochloride in shortage right now?
- No. FDA does not currently list Buprenorphine hydrochloride and naloxone hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Buprenorphine hydrochloride and naloxone hydrochloride?
- 4 companies have marketed Buprenorphine hydrochloride and naloxone hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Buprenorphine hydrochloride and naloxone hydrochloride cost?
- The typical pharmacy pays about $10.52 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.