The short version
13 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0231 per mL over the past year.
Market view
guaifenesin and dextromethorphan hydrobromide
39 marketed package NDCs · 13 active manufacturers
Most dispensed: 10 mg/5mL; 100 mg/5mL · Syrup · #237 mL/bottle, plastic · 600 mg; 30 mg · Tablet, Extended Release · #2 blister packs/carton / 20 tablet, extended release in 1 blister pack · 600 mg; 30 mg · Tablet, Extended Release · #1 blister pack/carton / 20 tablet, extended release in 1 blister pack · 600 mg; 30 mg · Tablet, Extended Release · #1 pouch/carton / 2 tablet, extended release in 1 pouch
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $0.0231 · middle half $0.0231–$0.0231 · full range $0.0231–$0.0231 · 2 products · 13 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for guaifenesin and dextromethorphan hydrobromide, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Mucinex DMSep 3, 2026Mfr exitedA-S Medication Solutions · guaifenesin and dextromethorphan hydrobromide
- Mucinex DMSep 3, 2026New productSelect Consumer Group
- Mfr exitedRite-Aid · guaifenesin and dextromethorphan hydrobromide
- Mucinex DM Maximum StrengthSep 2, 2026Mfr exitedReckitt Benckiser LLC · guaifenesin and dextromethorphan hydrobromide
- Mfr exitedCvs Pharmacy, Inc · guaifenesin and dextromethorphan hydrobromide
- Mucinex DM Maximum StrengthSep 2, 2026Mfr exitedA-S Medication Solutions · guaifenesin and dextromethorphan hydrobromide
- Mucinex DMSep 2, 2026Mfr exitedSportpharm LLC · guaifenesin and dextromethorphan hydrobromide
- Mucinex DMSep 2, 2026Mfr exitedSelect Consumer Group · guaifenesin and dextromethorphan hydrobromide
- Mucinex DMSep 2, 2026Mfr exitedReckitt Benckiser LLC · guaifenesin and dextromethorphan hydrobromide
- Guaifenesin DMSep 2, 2026Mfr exitedPD-Rx Pharmaceuticals, Inc. · guaifenesin and dextromethorphan hydrobromide
Same drug class
Other molecules FDA puts in Uncompetitive N-methyl-D-aspartate Receptor Antagonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- acetaminohpen, dextromethorphan hydrobromide· 1 maker
- acetaminophen 325 mg and dextromethorphan hbr 10 mg oral liquid day time kids· 1 maker
- acetaminophen 325 mg dextromethorphan hbr 10 mg phenylephrine hci 5 mg· 1 maker
- acetaminophen 325 mg dextromethorphan hbr 15 mg doxylamine succinate 6.25 mg· 1 maker
- acetaminophen 325 mg, dextromethorphan hbr 15 mg, doxylamine succinate 6.25 mg· 1 maker
- acetaminophen 650 mg, dextromethorphan hbr 20 mg, guaifenesin 400 mg, phenylephrine hcl 10 mg· 1 maker
- acetaminophen chlorpheniramine maleate dextromethorphan hydrobromide phenylepherine hydrochloride· 1 maker
- acetaminophen dextromethorphan hbr doxylamine succinate phenylephrine hci· 1 maker
- acetaminophen dextromethorphan hbr guaifenesin, phenylephrine hcl· 1 maker
- acetaminophen-chlorpheniramine maleate-dextromethorphan hbr-guaifenesin-phenylephrine hcl· 1 maker
- acetaminophen-dextromethorphan hbr-phenylephrine hcl-chlorpheniramine maleate· 1 maker
- acetaminophen, chlorpheniramine malaeate, dextromethorphan hydrobromide, phenylephrine hydrochloride· 1 maker
Common questions
- Is Guaifenesin and dextromethorphan hydrobromide in shortage right now?
- No. FDA does not currently list Guaifenesin and dextromethorphan hydrobromide in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Guaifenesin and dextromethorphan hydrobromide?
- 13 companies have marketed Guaifenesin and dextromethorphan hydrobromide in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Guaifenesin and dextromethorphan hydrobromide cost?
- The typical pharmacy pays about $0.0231 per mL, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.