The short version
21 companies supply this market — deep enough that no single failure threatens the supply.
Market view
irinotecan hydrochloride
47 marketed package NDCs · 21 active manufacturers
Most dispensed: 20 mg/mL · Injection, Solution · #1 vial, single-dose/carton / 2 ml in 1 vial, single-dose · 20 mg/mL · Injection, Solution · #1 vial, single-dose/carton / 5 ml in 1 vial, single-dose · 20 mg/mL · Injection, Solution · #1 vial, single-dose/carton / 15 ml in 1 vial, single-dose · 20 mg/mL · Injection · #1 vial, single-dose/carton / 5 ml in 1 vial, single-dose
Same drug class
Other molecules FDA puts in Topoisomerase Inhibitor, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
Common questions
- Is Irinotecan hydrochloride in shortage right now?
- No. FDA does not currently list Irinotecan hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Irinotecan hydrochloride?
- 21 companies have marketed Irinotecan hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
Shortage reports for this molecule
- Planned discontinuation — Irinotecan Hydrochloride, Injection, 100 mg/5 mL (NDC 25021-230-05)Sep 26, 2025
- Planned discontinuation — Irinotecan Hydrochloride, Injection, 40 mg/2 mL (NDC 25021-230-02)Sep 26, 2025
- Planned discontinuation — Irinotecan Hydrochloride, Injection, 20 mg/1 mL (NDC 45963-614-51)Aug 4, 2025
- Planned discontinuation — Irinotecan Hydrochloride, Injection, 20 mg/1 mL (NDC 45963-614-55)Aug 4, 2025
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.