The short version
10 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0288 per unit over the past year.
Market view
metformin er 500 mg
51 marketed package NDCs · 10 active manufacturers
Most dispensed: METFORMIN HYDROCHLORIDE 500 mg · Tablet, Extended Release · #90 tablet, extended releases/bottle · METFORMIN HYDROCHLORIDE 500 mg · Tablet, Extended Release · #100 tablet, extended releases/bottle · METFORMIN HYDROCHLORIDE 500 mg · Tablet, Extended Release · #60 tablet, extended releases/bottle · METFORMIN HYDROCHLORIDE 500 mg · Tablet · #1000 tablets/bottle
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $0.0288 · middle half $0.0288–$0.0288 · full range $0.0288–$0.0288 · 6 products · 10 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for metformin er 500 mg, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- Metformin ER 500 mgAug 19, 2026Price downNADAC $0.02932 → $0.02879 per unit (-1.81%)
- MetforminAug 19, 2026Price downNADAC $0.02932 → $0.02879 per unit (-1.81%)
- MetforminAug 19, 2026Price downNADAC $0.02932 → $0.02879 per unit (-1.81%)
- MetforminAug 19, 2026Price downNADAC $0.02932 → $0.02879 per unit (-1.81%)
- MetforminAug 19, 2026Price downNADAC $0.02932 → $0.02879 per unit (-1.81%)
- MetforminAug 19, 2026Price downNADAC $0.02932 → $0.02879 per unit (-1.81%)
- Metformin ER 500 mgJul 22, 2026Price downNADAC $0.02979 → $0.02932 per unit (-1.58%)
- MetforminJul 22, 2026Price downNADAC $0.02979 → $0.02932 per unit (-1.58%)
- MetforminJul 22, 2026Price downNADAC $0.02979 → $0.02932 per unit (-1.58%)
- MetforminJul 22, 2026Price downNADAC $0.02979 → $0.02932 per unit (-1.58%)
Same drug class
Other molecules FDA puts in Biguanide, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- empagliflozin, linagliptin, metformin hydrochloride· 1 maker
- empagliflozin, metformin hydrochloride· 1 maker
- metformin hydrochloride tablets· 1 maker
- pioglitazole and metformin hydrochloride· 1 maker
- pioglitazone hcl and metformin hcl· 1 maker
- saxagliptin and metformin· 1 maker
- saxagliptin and metformin hydrochloride· 1 maker
- canagliflozin and metformin hydrochloride· 2 makers
- empagliflozin and metformin hydrochloride· 2 makers
- ertugliflozin and metformin hydrochloride· 2 makers
- glipizide and metformin hcl· 3 makers
- metformin hydrochloride extended-release tablets· 3 makers
Common questions
- Is Metformin er 500 mg in shortage right now?
- No. FDA does not currently list Metformin er 500 mg in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Metformin er 500 mg?
- 10 companies have marketed Metformin er 500 mg in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Metformin er 500 mg cost?
- The typical pharmacy pays about $0.0288 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.