The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price is down 19% over the past year, to $16.68 per unit.
Market view
naloxone hydrochloride nasal
6 marketed package NDCs · 3 active manufacturers
Most dispensed: NALOXONE HYDROCHLORIDE 4 mg/.1mL · Spray · #2 vial, single-doses/carton / .1 ml in 1 vial, single-dose · NALOXONE HYDROCHLORIDE 4 mg/.1mL · Spray · #1 case/carton / 2 vial, single-dose in 1 case / .1 ml in 1 vial, single-dose
Price range and competition
RSS: changes for this drugEvery company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $16.68 · middle half $16.68–$16.68 · full range $16.68–$16.68 · 2 products · 3 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for naloxone hydrochloride nasal, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
Same drug class
Other molecules FDA puts in Opioid Antagonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- buprenorphine hydrochloride, naloxone hydrochloride· 1 maker
- naldemedine· 1 maker
- nalmefene hydrochloride injection· 1 maker
- naloxone hci· 1 maker
- naltrexone hydrochloride and bupropion hydrochloride· 1 maker
- narcan naloxone hci· 1 maker
- narcan naloxone hcl· 1 maker
- olanzapine and samidorphan l-malate· 1 maker
- pentazocine and naloxone· 1 maker
- naloxone· 2 makers
- pentazocine hydrochloride and naloxone hydrochloride· 2 makers
- nalxone hydrochloride· 3 makers
Common questions
- Is Naloxone hydrochloride nasal in shortage right now?
- No. FDA does not currently list Naloxone hydrochloride nasal in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Naloxone hydrochloride nasal?
- 3 companies have marketed Naloxone hydrochloride nasal in the last 30 days, according to the FDA NDC Directory. That is a thin market — if one stops making it, supply is at risk quickly. Every manufacturer and package is listed on this page.
- What does Naloxone hydrochloride nasal cost?
- The typical pharmacy pays about $16.68 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.