DrugDashboards

Reyvow

lasmiditan · LASMIDITAN 100 mg/1 · Tablet · Oral · Eli Lilly and Company

NDC 00002-4491-08 · 2 BLISTER PACK in 1 CARTON / 4 TABLET in 1 BLISTER PACK · NDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $88.77 per unit over the past year. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$88.77per EAinvoice-surveyed acquisition cost · May 20, 2026
  • Part D plans paid (avg)$91.20per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$86.44per unitnegotiated price across 41 plans — before rebates · Oct 1, 2025
  • Federal ceiling (Big4)$69.22per unitEli Lilly & Company · Jan 1, 202678% of what pharmacies pay — a deeper discount than 62% of drugs with this benchmark

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$86.44per unit
middle half $84.43$87.59 · 41 plans · Oct 1, 2025
Est. net of rebates
$51.86–$64.83
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
1%of plans cover it
tier 4 · prior auth 85% · step therapy 15% · qty limit 100%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 8 quarters since 2024.

NADAC price per unit

$0$50.00$100.00May 2020Sep 2026$88.77
29 price points · per EA · held since Invalid DateSource: CMS NADAC

Estimated fill cost

#30 count
$2663.14
#90 count
$7989.43

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$2.9M
4,367 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

30Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 2 active manufacturers+20
  • manufacturer plans to discontinue+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for lasmiditan (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA211280
TE code
Approval date
Jan 31, 2020
Patents / exclusivity
11 patents, 0 exclusivities
TypeNumber / codeExpires
patent12071423Jul 6, 2040
patent12071423Jul 6, 2040
patent11053214Dec 5, 2037
patent11053214Dec 5, 2037
patent11053214Dec 5, 2037
patent12257246Jul 7, 2030
patent12257246Jul 7, 2030
patent12257246Jul 7, 2030
patent7423050Feb 17, 2028
patent7423050Feb 17, 2028
patent7423050Feb 17, 2028

Shortage history

  • Planned discontinuation Reyvow, Tablet, 100 mg (NDC 0002-4491-08)Nov 3, 2025
  • Planned discontinuation Reyvow, Tablet, 100 mg (NDC 0002-4491-61)Nov 3, 2025
  • Planned discontinuation Reyvow, Tablet, 100 mg (NDC 0002-4491-62)Nov 3, 2025
  • Planned discontinuation Reyvow, Tablet, 50 mg (NDC 0002-4312-08)Nov 3, 2025
  • Planned discontinuation Reyvow, Tablet, 50 mg (NDC 0002-4312-61)Nov 3, 2025
  • Planned discontinuation Reyvow, Tablet, 50 mg (NDC 0002-4312-62)Nov 3, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of lasmiditan (Tablet)

LabelerStrengthFirst seenLast seen
Eli Lilly and CompanyLASMIDITAN 100 mg/1Jul 15, 2026Sep 2, 2026
Eli Lilly and CompanyLASMIDITAN 50 mg/1Jul 15, 2026Sep 2, 2026
Lilly del Caribe, Inc.LASMIDITAN 100 mg/1Jul 15, 2026Sep 2, 2026
Lilly del Caribe, Inc.LASMIDITAN 50 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Reyvow — NDC 00002-4491-08," retrieved September 3, 2026, https://drugdashboards.com/drug/00002449108.

Free to cite with attribution — see how the data is put together.