DrugDashboards

Insulin Lispro

Insulin lispro · INSULIN LISPRO 100 [iU]/mL · Injection, Solution · Intravenous; Subcutaneous · Eli Lilly and Company

NDC 00002-7737-01 · 1 VIAL in 1 CARTON / 10 mL in 1 VIAL · BLA · View full market →

The short version

6 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $2.40 per mL over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.4% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$2.40per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicare Part B pays (ASP+6%)$3.06per billing unit (50 UNITS)HCPCS J1817 · Jul 1, 2026
  • Part D plans paid (avg)$2.49per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$2.41per unitnegotiated price across 2,959 plans — before rebates · Apr 1, 2026
  • Federal ceiling (Big4)$18.71per package of 10MLEli Lilly & Company · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$2.41per unit
middle half $2.39$2.56 · 2,959 plans · Apr 1, 2026
Est. net of rebates
$1.44–$1.81
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
54%of plans cover it
tier 3 · prior auth 4% · step therapy 0% · qty limit 7%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$5.00$10.00$15.00Jul 2020Sep 2026$2.40
73 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$25.00
Reported to Texas DSHS · 2026 annual filing · Eli Lilly and Company

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 50 UNITS
$3.062
HCPCS J1817 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$35.5M
527,159 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.4%chance of a new FDA shortage posting for insulin lispro (injectable) in the next 90 days

sterile injectable · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 3 across plans
  • Costs ≥ $950/fill · avg $58.20 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
BLA020563
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Insulin Lispro Junior KwikPen, Injection, 100 [iU]/1 mL (NDC 0002-7752-05)Sep 1, 2026
  • Planned discontinuation Humalog, Injection, U-100 Tempo Pen (NDC 0002-8213-05)Oct 24, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Insulin lispro (Injection, Solution)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsINSULIN LISPRO 100 [iU]/mLJul 15, 2026Sep 3, 2026
Eli Lilly and CompanyINSULIN LISPRO 100 [iU]/mLJul 15, 2026Sep 3, 2026
Lilly FranceINSULIN LISPRO 100 [iU]/mLJul 15, 2026Sep 3, 2026
Eli Lilly Italia SPAINSULIN LISPRO 100 [iU]/mLJul 15, 2026Sep 2, 2026
Lilly FranceINSULIN LISPRO 200 [iU]/mLJul 15, 2026Sep 2, 2026
Remedyrepack Inc.INSULIN LISPRO 100 U/mLJul 15, 2026Sep 2, 2026
Eli Lilly and CompanyINSULIN LISPRO 200 [iU]/mLJul 15, 2026Aug 31, 2026
Sanofi-Aventis U.S. LLCINSULIN LISPRO 100 U/mLJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Insulin Lispro — NDC 00002-7737-01," retrieved September 3, 2026, https://drugdashboards.com/drug/00002773701.

Free to cite with attribution — see how the data is put together.