The short version
4 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Opdivo
nivolumab · NIVOLUMAB 10 mg/mL · Injection · Intravenous · E.R. Squibb & Sons, L.L.C.
NDC 00003-3774-12 · 1 VIAL, SINGLE-DOSE in 1 CARTON / 10 mL in 1 VIAL, SINGLE-DOSE · BLA · View full market →
One drug, every price
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
ⓘ How this was built
Data sources
- CMS NADAC (pharmacy acquisition, weekly)
- CMS Part B ASP quarterly payment limits
- CMS Maximum Fair Prices (IRA negotiated, NDC-level)
- Medicare Part D Spending by Drug (data.cms.gov, name-matched)
- VA FSS / Big4 federal contract prices (va.gov, twice monthly)
- ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
- California SB-17 WAC filings (list price, per package)
Method
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
- Medicare Part B pays (ASP+6%)$34.22per billing unit (1 MG)HCPCS J9299 · Jul 1, 2026
- Part D plans paid (avg)$308.87per dosage unitgross, before rebates — matched by drug name · 2024
- Federal ceiling (Big4)$2,391.27per package of 1X10MLBristol-Myers Squibb Company · Jan 1, 2026
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$3,375.79
Reported to Texas DSHS · 2026 annual filing · Bristol-Myers Squibb Company & Subsidiaries
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Medicare Part B (ASP)
Payment limit per 1 MG
$34.222
HCPCS J9299 · Jul 1, 2026 quarter · typically ASP + 6%
Medicaid spend (2025)
$12.0M
2,425 prescriptions paid by Medicaid nationally · all Medicaid spend →
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 3 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill · avg $12,206.21 per prescription
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program
Regulatory
- Application
- BLA125554
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of nivolumab (Injection)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| E.R. Squibb & Sons, L.L.C. | NIVOLUMAB 10 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| Bristol-Myers Squibb Company | NIVOLUMAB 1 kg/kg | Jul 15, 2026 | Sep 2, 2026 |
| Lotte Biologics USA, LLC | NIVOLUMAB 1 kg/kg | Jul 15, 2026 | Sep 2, 2026 |
| Swords Laboratories Unlimited Company | NIVOLUMAB 1 kg/kg | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Opdivo — NDC 00003-3774-12," retrieved September 3, 2026, https://drugdashboards.com/drug/00003377412.
Free to cite with attribution — see how the data is put together.